@article{article_1529304, title={A Case of Iatrogenic Botulism with a Toxin of Unknown Formulation}, journal={Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi}, volume={20}, pages={241–243}, year={2025}, DOI={10.17517/ksutfd.1529304}, author={Koçtürk, Fatih}, keywords={iyatrojenik botulizm, botulinum toksin}, abstract={All serotypes block the release of the essential neurotransmitter acetylcholine at the neuromuscular junction, causing muscle paralysis. Cosmetological applications include a range of treatments, from correcting lines, wrinkles, and creases on the face, chin, neck, and chest area to dermatological applications such as hyperhidrosis. Botulinum toxin injections are generally well-tolerated and have few side effects. We present a case of botulism that was affected by Botox treatment of the forehead and axillae in an external clinic. Ten days later, Botox was administered to the soles of the feet for sweating. The patient, whose complaints had increased over the past 2 days, contacted our emergency department with these complaints. The patient, who was admitted to the neurology clinic with the preliminary diagnosis of iatrogenic botulism and whose vitals were stable the patients reported in the recent studies developed a syndrome similar to botulism after intramuscular injections of therapeutic doses of onabotulinum toxin derived from two different batches of the drug. In the first patient, these symptoms occurred after only one dose, while in the second patient, they occurred after five years of regular treatment with the toxin. Clinically detectable weakness was present in the extraocular, bulbar, trunk, and limb muscles, and EMG changes were recorded in all muscles tested. The muscle weakness and EMG changes resolved a few weeks later.}, number={3}, publisher={Kahramanmaraş Sütçü İmam Üniversitesi}