@article{article_1529760, title={COVID-19-Related Multisystem Inflammation Syndrome In Children: Cardiovascular And Coronary Assessment}, journal={Samsun Medical Journal}, volume={1}, pages={8–15}, year={2023}, author={Elbir Şahin, Ayşegül}, keywords={Çocuklar, Koroner arter, Sol ventrikül fonksiyonu, SARS koronavirüsü}, abstract={Objective: Despite the global attention directed towards coronavirus-19 (COVID-19) disease, a comprehensive understanding of the condition remains elusive. The cardiovascular implications, pivotal in this disease, are largely derived from case series and reviews, lacking the depth of prospective studies. This single-arm observational study aims to fill this void by examining the coronary arteries and assessing the systolic/diastolic functions of the left ventricle in children diagnosed with “Multisystem Inflammatory Syndrome” associated with COVID-19 (MIS-C). Material and methods: We conducted a prospective study involving 36 MIS-C patients aged 0-18 years, focusing on cardiovascular involvement and tracking changes in the coronary arteries, as well as the systolic and diastolic functions of the left ventricle during the disease course. Results: Among the patients, 11.1% exhibited endocarditis, 5.5% myocarditis, 0% pericardial effusion, 16.6% coronary dilation, and 0% coronary aneurysm. Even in patients without cardiovascular involvement, subtle changes were noted, including a decrease in systolic and diastolic left ventricular function and an increase in the z score of the left main coronary artery. Despite these observations, all patients experienced full recovery upon discharge, with no reported deaths or complications. Conclusion: This study underscores the rarity of cardiovascular manifestations in MIS-C, often following a benign course, particularly with prompt treatment. Even in the absence of clinical symptoms, MIS-C affects the left ventricular function and the left main coronary artery.}, number={1}, publisher={Samsun Üniversitesi}