@article{article_1550129, title={The Relationship of Basal LH/FSH Ratio and Basal Estradiol Level with Oocyte and Embryo Quality in Cases with Polycystic Ovary Syndrome}, journal={Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi}, volume={22}, pages={234–240}, year={2025}, DOI={10.38136/jgon.1550129}, author={Akdöner, Aslı and Yavuz, Onur and Mankan, Kadir Alper and Balci, Umay and Kovalı Sezer, Müge and Doğan, Sultan Seda and Okyay, Emre and Çağlıyan, Erkan and Doğan, Ömer Erbil and Celiloglu, Murat and et al.}, keywords={Oosit matürasyonu, Embriyo kalitesi, İn vitro fertilizasyon}, abstract={Aim: We aim to explore how the basal LH/FSH ratio and basal E2 levels correlate with the quality and number of oocytes and embryos, as well as with clinical pregnancy outcomes in patients with polycystic ovary syndrome. Materials and Methods: Cases with polycystic ovary syndrome between the ages of 18-35 were involved in the study. The characteristic features of the cases, laboratory values, total stimulation duration and dose, endometrium thickness and dominant follicle number on the ovulation trigger day, maturity and number of oocytes, quality and number of embryos, number of transferred embryos, implantation rate and clinical pregnancy rates were recorded from the hospital registry system and files. SPSS version 26.0 is used for analyzing the data. Results: The average number of oocytes obtained from all cases was 15, MII oocyte rate was 84.6%, embryo number was 8 and high quality embryo rate was 66%. MII oocyte rate and embryo number were higher in group 2 (p=0.005 and p=0.003). A negative relation was found between basal E2 levels and M2 oocyte rates (r=-0.1, p=0.02). No notable correlation was detected between basal E2 levels and good quality embryo rate (r=0.05, p=0.5). Conclusion: It was found that in polycystic ovary syndrome cases with a basal LH/FSH ratio ≥ 1.5, mature oocyte ratio was higher and basal E2 level was inversely related to mature oocyte ratio. However, it was determined that these effects were not reflected in embryo quality and clinical pregnancy results.}, number={2}, publisher={T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi}