TY - JOUR T1 - The Impact of Low Birth Weight and Gestational Age on Premature Retinopathy Outcomes TT - Düşük Doğum Ağırlığı ve Gebelik Yaşının Prematüre Retinopatisi Üzerindeki Etkisi AU - Mutaf, Çağrı AU - Reyhan, Ali Hakim AU - Uzun, İrfan AU - Yüksekyayla, Funda AU - Şimşek, Ali PY - 2025 DA - March Y2 - 2025 DO - 10.35440/hutfd.1585350 JF - Harran Üniversitesi Tıp Fakültesi Dergisi PB - Harran Üniversitesi WT - DergiPark SN - 1304-9623 SP - 26 EP - 31 VL - 22 IS - 1 LA - en AB - Background: The study aimed to investigate the incidence and treatment of retinopathy of prematu-rity (ROP) in premature infants, focusing on its relationship with gestational age and birth weight.Materials and Methods: This retrospective study analyzed 1101 infants with a gestational age of 34 weeks or less and/or a birth weight of 1700 grams or less, screened for ROP between 2021 and 2023.Results: Fifty-five infants required ROP treatment. ROP incidence was higher in lower birth weight and earlier gestational age groups. Among infants weighing 1000 grams or less, 56.1% developed ROP, compared to 43% in the 1001-1250 gram category and 28.1% in the 1251-1700 gram category. For gestational age, 53.2% of infants less than 27 weeks, 26.8% of 27-34 weeks, and 12.7% of over 34 weeks developed ROP.Conclusions: Premature infants, especially those with very low birth weight and early gestational age, are at high risk for ROP, necessitating comprehensive screening and timely intervention. KW - Retinopathy of prematurity KW - Birth weight KW - Gestational age KW - Laserphotocoagulation. N2 - Amaç: Çalışmanın amacı, prematüre bebeklerde prematüre retinopatisi (ROP) insidansı ve tedavisini araştırmak, özellikle gestasyonel yaş ve doğum ağırlığı ile ilişkisini incelemektir.Materyal ve Metod: Bu retrospektif çalışma, 2021 ve 2023 yılları arasında ROP için taranan, gestas-yon yaşı 34 hafta veya daha az ve/veya doğum ağırlığı 1700 gram veya daha az olan 1101 bebeği analiz etmiştir.Bulgular: Elli beş bebek ROP tedavisi gerektirmiştir. ROP insidansı, daha düşük doğum ağırlığı ve daha erken gestasyonel yaş gruplarında daha yüksekti. 1000 gram veya daha az ağırlığındaki bebeklerin %56,1'i ROP geliştirirken, 1001-1250 gram kategorisinde %43 ve 1251-1700 gram kategorisinde %28,1 ROP geliştirmiştir. Gestasyonel yaşa göre, 27 haftadan küçük bebeklerin %53,2'si, 27-34 hafta arası bebeklerin %26,8'i ve 34 haftadan büyük bebeklerin %12,7'si ROP geliştirmiştir.Sonuç: Prematüre bebekler, özellikle çok düşük doğum ağırlığı ve erken gestasyonel yaşa sahip olan-lar, ROP için yüksek risk altındadır ve kapsamlı tarama ve zamanında müdahale gereklidir. CR - 1. Zhang L et al. Retinopathy of Prematurity—Targeting Hypoxic and Redox SignalingPathways. Antioxidants (Basel). 2024;13(2):148. doi: 10.3390/antiox13020148. CR - 2. Dogra MR, Katoch D, Dogra M. An update on retinopathy of prematurity (ROP). Indian J Pediatr. 2017;84(12):930-6. CR - 3. Terry TL. Extreme prematurity and fibroblastic overgrowth of persistent vascular sheath behind each crystalline lens: I, pre-liminary report. Am J Ophthalmol. 2018;25:203-4. CR - 4. 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