TY - JOUR T1 - Efficacy and safety of double balloon enteroscopy in patients with Peutz-Jeghers Syndrome: Single center experience TT - Peutz- Jeghers sendromu olan hastalarda çift balon enteroskopinin etkinliği ve güvenliğinin değerlendirilmesi: Tek merkez deneyimi AU - Yüksel, Mahmut AU - Yeşil, Bayram AU - Erdoğan, Çağdaş AU - Turan Gökçe, Dilara AU - Bacaksız, Ferhat AU - Macif, Alper AU - Tenlik, İlyas AU - Öztürk, Ömer AU - Arı, Derya AU - Tayfur Yürekli, Öykü AU - Akdoğan Kayhan, Meral AU - Gökcan, Hale PY - 2024 DA - December Y2 - 2024 DO - 10.17941/agd.1591271 JF - Akademik Gastroenteroloji Dergisi PB - Türk Gastroenteroloji Vakfı WT - DergiPark SN - 1303-6629 SP - 93 EP - 100 VL - 23 IS - 3 LA - en AB - Background and Aims: Our understanding of the clinical outcomes of double balloon enteroscopy in individuals with Peutz-Jeghers syndrome is limited. The purpose of this study is to assess double balloon enteroscopy’s effectiveness and safety in managing small intestinal polyps in Peutz-Jeghers syndrome patients. Materials and Methods: Data from 16 Peutz-Jeghers syndrome patients who underwent double balloon enteroscopy at our center between January 2007 and March 2020 have been collected. The study included patients with polyps larger than 1 cm in diameter. Results: Sixteen patients with Peutz-Jeghers syndrome underwent a total of 79 double balloon enteroscopy procedures, and a total of 469 polyps larger than 1 cm were found in 76 oral/anal double balloon enteroscopies. Over 80 polyps seen in the small intestinal segments were removed using endoscopic polypectomy during intraoperative double balloon enteroscopy. Four patients underwent intraoperative enteroscopy in addition to double balloon enteroscopy and over 200 polyps were removed via endoscopic polypectomy. A total of 19 complications which was related with procedures and anesthesia occurred either during or after the 79 double balloon enteroscopy procedures. All procedure related complications were treated with minimally invasive methods. After double balloon enteroscopy, two patients underwent surgery (one with invagination, the other with adhesion ileus). Conclusion: Double balloon enteroscopy can be considered a reliable and effective method in the diagnosis and long-term follow-up of patients with Peutz-Jeghers syndrome. KW - Double balloon enteroscopy KW - Peutz-Jeghers syndrome KW - polyp N2 - Giriş ve Amaç: Peutz-Jeghers sendromlu bireylerde çift balon enteroskopinin klinik sonuçları hakkındaki bilgilerimiz sınırlıdır. Bu çalışmanın amacı, Peutz-Jeghers sendromlu hastalarda ince bağırsak poliplerinin yönetiminde çift balon enteroskopinin etkinliğini ve güvenliğini değerlendirmektir. Gereç ve Yöntem: Ocak 2007 ile Mart 2020 tarihleri arasında merkezimizde çift balon enteroskopi uygulanan 16 Peutz-Jeghers sendromlu hastanın verileri toplandı. Çalışmaya çapı 1 cm'den büyük polipleri olan hastalar dahil edildi. Bulgular: Peutz-Jeghers sendromlu 16 hastaya toplam 79 çift balon enteroskopi prosedürü uygulandı ve 76 oral/anal çift balon enteroskopide 1 cm'den büyük toplam 469 polip bulundu. İnce bağırsak segmentlerinde görülen 80'den fazla polip, intraoperatif çift balon enteroskopi sırasında endoskopik polipektomi kullanılarak çıkarıldı. Dört hastaya çift balon enteroskopiye ek olarak intraoperatif enteroskopi uygulanmış ve endoskopik polipektomi ile 200'den fazla polip çıkarılmıştır. 79 çift balon enteroskopi prosedürü sırasında veya sonrasında prosedürler ve anestezi ile ilgili toplam 19 komplikasyon meydana gelmiştir. Prosedürle ilgili tüm komplikasyonlar minimal invaziv yöntemlerle tedavi edilmiştir. 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