TY  - JOUR
T1  - Investigation of Normalized Volume Ratios of Motor and Sensory Cortices on Magnetic Resonance Images in Parkinson's Disease Patients: An Automatic Brain Segmentation Study
AU  - Nahir, Mert
AU  - Doğan, Berna
AU  - Sümbül, Orhan
PY  - 2025
DA  - January
Y2  - 2025
DO  - 10.37990/medr.1594776
JF  - Medical Records
JO  - Med Records
PB  - Tıbbi Kayıtlar Derneği
WT  - DergiPark
SN  - 2687-4555
SP  - 245
EP  - 250
VL  - 7
IS  - 1
LA  - en
AB  - Aim: This study evaluates structural changes in the normalized volume ratios of the motor and sensory cortices in Parkinson’s patients and compares these changes with healthy individuals to assess the disease's impact on brain structure.Material and Method: The study included 55 Parkinson’s patients (14 females, 41 males) and 28 control subjects (7 females, 21 males). The volumes of the precentral gyrus, paracentral lobulus, and postcentral gyrus were calculated using the BrainSuite automated segmentation software. Regional gray matter volumes were normalized by dividing them by the intracranial volume, and these normalized values were used for comparisons. Volumetric analyses were conducted on the precentral gyrus, postcentral gyrus, and paracentral lobulus to assess their morphological changes associated with Parkinson's disease.Results: Results: In the left hemisphere, the normalized gray matter volume ratios of the postcentral gyrus were found to be lower in Parkinson’s patients (0.82%±0.09) compared to the control group (0.88%±0.09) (p
KW  - Precentral gyrus
KW  - paracentral lobulus
KW  - postcentral gyrus
KW  - intracranial volume
KW  - BrainSuite
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UR  - https://doi.org/10.37990/medr.1594776
L1  - http://dergipark.org.tr/tr/download/article-file/4409518
ER  -