TY  - JOUR
T1  - Dopamin Sekrete Eden Baş ve Boyun Paragangliomaları: Literatür İncelemesi ve Olgu Sunumu
TT  - Dopamine-Secreting Head and Neck Paragangliomas: Literature Review and A Case Report
AU  - Şivetoğlu, Aleyna
AU  - Baklacı, Deniz
AU  - Erdem, Duygu
AU  - Saka, Seda Nur
AU  - Kılıç, Gökhan Furkan
PY  - 2025
DA  - August
Y2  - 2025
DO  - 10.29058/mjwbs.1598103
JF  - Medical Journal of Western Black Sea
JO  - Med J West Black Sea
PB  - Zonguldak Bülent Ecevit Üniversitesi
WT  - DergiPark
SN  - 2822-4302
SP  - 135
EP  - 141
VL  - 9
IS  - 2
LA  - tr
AB  - Bu çalışmanın amacı, literatürde baş boyunda dopamin salgılayan paraganglioma olgularını incelemek ve yalnızca dopamin salgılayanjuguler ve karotis cisim paraganglioma tanılı bir hastayı sunmaktır. Dopamin fazlalığının baş boyun paragangliomalarında sık görüldüğü vedopamin ölçümünün hastaların takibinde faydalı olabileceği düşünülmektedir 1983-2024 yılları arasında literatürde baş-boyun bölgesinde yer alan ve ağırlıklı olarak dopamin salgılayan 16 paraganglioma olgusuincelenmiş ve bir olgu sunularak literatüre katkıda bulunulmuştur.Baş boyunda dopamin salgılayan paragangliomalarda en sık görülen semptom hipertansiyon olarak bulunmuş; bunu işitme kaybı, disfaji,disfoni, tinnitus izlemiştir. Olguların medyan yaşı 46,3 olup, erkek-kadın oranı 1,6:1’dir. Tedavi yöntemleri arasında 10 olguda cerrahi, 2olguda radyoterapi, 1 olguda konservatif tedavi uygulanmış, 3 olguda tedavi kayıtlarına ulaşılamamıştır. Olgumuzda da hipertansiyon, işitmekaybı, disfoni, tinnitus ve fasiyal paralizi mevcuttu ve radyoterapi tedavisi aldı.Dopamin salgılayan baş boyun paragangliomaları genellikle basıya bağlı semptom verir, tanı anında hastalığa bağlı çeşitli morbiditelerolabilir. Dopamin ölçümleri, bu tümörlerin tanı ve takibi için faydalı olabilir.
KW  - Baş ve boyun
KW  - dopamin
KW  - paraganglioma
N2  - This study aims to review the cases of dopamine-secreting paragangliomas of the head and neck in the literature and to present a patientdiagnosed with a jugular and carotid body paraganglioma secreting only dopamine. It is considered that dopamine excess is common inhead and neck paragangliomas and dopamine measurement may be useful in the follow-up of patients.Between 1983 and 2024, 16 cases of predominantly dopamine-secreting paragangliomas located in the head and neck region were reviewedin the literature and one case is presented to contribute to the existing knowledge.Hypertension is the most common symptom in dopamine-secreting paragangliomas of the head and neck, followed by hearing loss, dysphagia,dysphonia and tinnitus. The median age was 46.3 years and the male to female ratio was 1.6:1. Treatment modalities included surgeryin 10 cases, radiotherapy in 2 cases, conservative treatment in 1 case and no treatment record was available in 3 cases. In our case, thepatient presented with hypertension, hearing loss, dysphonia, tinnitus and facial paralysis and was treated with radiotherapy.Dopamine-secreting head and neck paragangliomas are usually symptomatic due to compression, and there may be various morbidities associatedwith the disease at the time of diagnosis. Dopamine measurements may be useful for the diagnosis and follow-up of these tumors.
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UR  - https://doi.org/10.29058/mjwbs.1598103
L1  - https://dergipark.org.tr/tr/download/article-file/4424897
ER  -