TY  - JOUR
T1  - Inflammatory Markers, Impulsivity and Aggression in Fibromyalgia Patients
TT  - Fibromiyalji Hastalarında İnflamatuvar Belirteçler, Dürtüsellik ve Saldırganlık
AU  - Uslu, Muhammed Fuad
AU  - Yıldırım Uslu, Emine
AU  - Yıldız, Sevler
AU  - Tabara, Muhammed Fatih
PY  - 2025
DA  - June
Y2  - 2025
DO  - 10.35440/hutfd.1600799
JF  - Harran Üniversitesi Tıp Fakültesi Dergisi
PB  - Harran Üniversitesi
WT  - DergiPark
SN  - 1304-9623
SP  - 205
EP  - 211
VL  - 22
IS  - 2
LA  - en
AB  - Background: Psychosomatic mechanisms are recognized to play a role in fibromyalgia (FMS), particularly in its manifestation of chronic pain. This study aimed to explore the association between hematological and biochemical test results and levels of impulsivity and aggression in patients with FMS.Materials and Methods: The study comprised 146 women, including 73 healthy controls and 73 patients diagnosed with FMS. Hematological and biochemical test results were analyzed, and participants were assessed using Fibromyalgia Impact Questionnaire (FIQ), the Buss-Perry Aggression Questionnaire (BPAQ), and the Barratt Impulsiveness Scale-Short Form (BIS-11-SF).Results: The BIS-11-SF scale score for the FMS group was 58.67 ± 16.83, compared to 48.07 ± 15.43 for the control group (p < 0.001). Similarly, the BAQ score was significantly higher in the FMS group (71.95 ± 18.45) than in the control group (55.91 ± 16.86, p < 0.001). Moreover, a significant negative correlation was found between BMI and SII, SIRI, and NLR (p = 0.003, p = 0.038, and p = 0.001, respectively).Conclusion: Women with fibromyalgia are more impulsive and aggressive than the normal population. According to the results of our study, the parameters obtained from complete blood count cannot predict the levels of impulsivity and aggression.
KW  - Fibromyalgia
KW  - inflammatory markers
KW  - impulsivity
KW  - aggression
N2  - Amaç: Psikosomatik kökenli mekanizmaların kronik ağrı ile seyreden fibromiyalji (FMS) hastalığında görev aldığı bilinmektedir. Biz bu hasta grubunda hemogram ve biyokimya tetkikleri ile dürtüsellik ve saldırganlık arasındaki ilişkiyi incelemeyi amaçladık.Materyal ve Metod: Çalışmaya 73 sağlıklı kontrol grubu ve 73 FMS tanılı hasta olmak üzere 146 kadın dahil edildi. Hemogram ve biyokimya tetkik sonuçları değerlendirilen bu kişilere ayrıca Fibromiyalji Etki Anketi (FEA), Buss-Perry Saldırganlık Ölçeği (BAQ), Barratt Dürtüsellik Ölçeği Kısa Form (BIS-11-SF) ölçekleri uygulandı.Bulgular: Vaka grubunun BIS-11-SF ölçek puanı 58,67±16,83 iken kontrol grubunun ölçek puanı 48,07±15,43 olarak saptandı (p<0,001).  Benzer şekilde vaka grubunun BAQ puanı 71,95±18,45 iken kontrol grubunun ölçek puanı 55,91±16,86 olarak saptandı (p<0,001). BKI ile SII, SIRI ve NLR arasında negatif yönde anlamlı ilişki olduğu saptandı (0,003, 0,038, 0,001)Sonuç:Fibromiyalji tanılı kadınlar normal popülasyona göre daha dürtüsel ve daha saldırgandır. Çalışmamızın sonuçlarına göre tam kan sayımından elde edilen parametreler dürtüsellik ve saldırganlık düzeylerini yordayamamaktadır.
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UR  - https://doi.org/10.35440/hutfd.1600799
L1  - https://dergipark.org.tr/tr/download/article-file/4437440
ER  -