TY - JOUR T1 - Ürolitin-A’nın Non-Enfeksiyöz İshalli Buzağılarda Dışkı Skorları Üzerine Etkinliğinin Araştırılması TT - Investigation Of The Effectiveness Of Urolithin-A On Fecal Scores In Calves With Non-İnfectious Diarrhea AU - Alıç Ural, Deniz AU - Ural, Kerem AU - Paşa, Serdar AU - Gültekin, Mehmet AU - Erdoğan, Hasan AU - Erdoğan, Songül AU - Balıkçı, Cansu AU - Kizilkanat, Ayşe İdil PY - 2025 DA - April Y2 - 2025 DO - 10.58208/cphs.1607670 JF - Current Perspectives on Health Sciences JO - CPHS PB - Burdur Mehmet Akif Ersoy Üniversitesi WT - DergiPark SN - 2757-8585 SP - 39 EP - 46 VL - 6 IS - 1 LA - tr AB - Amaç: Bu araştırmada amaç, fonksiyonel gıda özelliğine sahip olan Ürolithin-a' (Ür-a)’nın enfeksiyözolmayan ishalli buzağılarda doğal tedavi katılımcısı olarak etki edip edemeyeceğini multidisiplinerolarak tespit etmektir. Gereç ve Yöntem: Bu amaçla 1 ila 28 günlük ishalli neonatal buzağılararasından seçilerek, non-enfeksiyöz etiyolojiye sahip olan 40 buzağı çalışmaya dahil edildi. Enfeksiyözve enfeksiyöz olmayan ishaller arasında ayırıcı tanı için mikrobiyolojik, parazitolojik ve virolojiklaboratuvar testlerine dayalı bir algoritma kullanıldı. Dışkı puanlaması 0 (normal kıvam) ile 3 (sıvıform) arasında bir ölçekle yapıldı. Ür-a, herhangi bir yan etki olmaksızın 10 ardışık gün boyunca 50mg/kg dozunda oral yoldan uygulandı. Bulgular: Ür-a uygulamasına ilişkin olarak dışkı skorları(ortalama±standart sapma) önceki başlangıç değerleri olan 1.826 ± 0.242'ye (p < 0,01) kıyasla 0'a düştü.Sonuç: Elde edilen veriler, bu ön sonuçların non-infeksiyöz ishalli buzağılarda Ür-a'nın gastrointestinalsağlığı destekleyici etkinliğine sahip olabileceğini gösterebilir. İleriki çalışmaların gerçekleştirilmesigerekliliği, bir sonraki çalışmamızın amacı olacaktır KW - Buzağı KW - ishal KW - non-enfeksiyöz KW - urolithin-a N2 - Aim: The aim of this study was to determine multidisciplinary whether Urolithin-a (Ur-a), which hasfunctional food properties, can be effective as a natural treatment agent in calves with non-infectiousdiarrhea. Materials and Methods: For this purpose, neonatal calves with diarrhea aged 1 to 28 daysand 40 calves selected with non-infectious etiology were included in the study. An algorithm based onmicrobiological, parasitological and virological laboratory tests was used for differential diagnosisbetween infectious and non-infectious diarrhea. Stool scoring was done on a scale from 0 (normalconsistency) to 3 (liquid form). Ur-a was administered orally at a dose of 50 mg/kg for 10 consecutivedays without any side effects. 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