@article{article_1621908, title={Ketogenic Diet and Cancer}, journal={Van Sağlık Bilimleri Dergisi}, volume={18}, pages={80–85}, year={2025}, DOI={10.52976/vansaglik.1621908}, author={Doğan, Duygu and Okumuş, Emine and Meydan, İsmet}, keywords={kanser, ketojenik diyet, antitümör, warburg etkisi}, abstract={The ketogenic diet is a diet implemented with high fat consumption and adequate protein by reducing glucose and increasing ketone bodies. Ketogenic diet; It is recommended as an effective intervention on diseases such as diabetes, obesity, cardiovascular diseases and cancer. The ketogenic diet is a diet with high fat and low protein by reducing glucose and increasing ketone bodies. Ketogenic diet; It is recommended as an effective intervention on diseases such as diabetes, obesity, cardiovascular diseases and cancer. In experimental models and clinical studies, the ketogenic diet has an antitumor effect by reducing energy sources to cells and preventing tumor growth. Cancer cells use the Warburg effect on ketogenic diet metabolism. Aerobically dominant glucose utilization may be a possible pathway to be targeted during cancer therapy. Research emphasizes that the integration of the ketogenic diet with the traditional treatment protocol will show positive results on the antitumor effect of chemotherapy. This review provides evidence for understanding the mechanism of action of the ketogenic diet on cancer treatment and its therapeutic use.}, number={1}, publisher={Van Yüzüncü Yıl Üniversitesi}