TY  - JOUR
T1  - Are Inflammatory Markers Useful in Determining The Anatomic Localisation of Colorectal Cancer? Immature Granulocytes and Red Cell Distributon Width.
TT  - Kolorektal Kanserin Anatomik Lokalizasyonun Belirlenmesinde İnflamatuar Belirteçler Faydalı Mıdır?: İmmatür Granulosit ve Kırmızı Hücre Dağılım Genişliği
AU  - Özdemir, Ümit
AU  - Baran, Necip Tolga
PY  - 2025
DA  - September
Y2  - 2025
DO  - 10.47482/acmr.1627472
JF  - Archives of Current Medical Research
JO  - Arch Curr Med Res
PB  - 14 Mart Tıbbiyeliler Derneği
WT  - DergiPark
SN  - 2717-9788
SP  - 157
EP  - 165
VL  - 6
IS  - 3
LA  - en
AB  - Background: There are embryological, clinicopathlogical, and prognostic differences between right and left colon tumours. The aim of this study was to investigate the diagnostic benefit of inflammatory markers in the differentiation of right and left colon cancers.Methods: Two groups of patients were formed as 71 (33.8%) with right colon cancer (RCC) and 139 (66.2%) with left colorectal cancer (LCRC). The groups were compared in respect of clinical characteristics, hemoglobin, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), systemic immune inflammation index (SII), immature granulocyte count (IGC), immature granulocyte percentage (IG%), and red blood cell distribution width percentage (RDW%).Results: The TNM grade, and NLR, PLR, SII, IGC, and IG% values were similar in both groups. In the RCC group, hemoglobin was determined to be lower than in the LCRC group (11.35 [6.40-16.40] vs. 13.00 [6.00-17.00] mg/dl), and RDW was higher (14.80% [11.90-27.90] vs. 13.70% [11.00-37.10]) (p=0.001, p=0.005, respectively). In ROC analysis, hemoglobin (AUC:0.640, p
KW  - Colorectal Cancer
KW  - Colorectal Cancer Localisation
KW  - Inflammatory markers
KW  - Immature Granulocytes
KW  - Red Cell Distribution Width
N2  - Arka Plan: Sağ ve sol kolon tümörleri arasında embriyolojik, klinikopatolojik ve prognostik farklar bulunur. Bu çalışmanın amacı sağ ve sol kolon kanserlerinin ayrılmasında inflamatuar belirteçlerin tanısal faydasının araştırılmasıdır.Yöntemler: Hastalar sağ kolon kanseri(RCC) n=71 ((33.8%)) ve sol kolorektal kanser(LCRC) (n =139 (66.2%)) olarak ikiye ayrıldı. Klinik özellikler, hemoglobin, nötrofil lenfosit oranı (NLR), platelet lenfosit oranı(PLR), Sistemik İmmün-inflamasyon İndeksi(SII), İmmatür Granulosit sayısı(IGC), İmmatür Granulosit yüzdesi (IG%), Kırmızı Hücre Dağılım Genişliği yüzdesi (RDW) parametreleri gruplar arasında karşılaştırıldı.Bulgular: Karşılaştırmada TNM evresi, NLR, PLR, SII, IGC ve IG% gruplar arasında benzerdir. RCC grubunda, hemoglobin düşük (11.35 (6.40 – 16.40) vs 13.00 (6.00 – 17.00) mg/dl), RDW yüksektir (14.80 %(11.90 – 27.90) vs 13.70% (11.00 – 37.10)), p=0.001 ve p=0.005 sırasıyla. ROC analizi hemoglobin(p
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UR  - https://doi.org/10.47482/acmr.1627472
L1  - https://dergipark.org.tr/tr/download/article-file/4554417
ER  -