TY  - JOUR
T1  - Is Serum Tryptase a Dependable Biomarker for Diagnosing and Tracking Rheumatoid Arthritis?
AU  - Topaloğlu, Mehmet Serhat
AU  - Devrimsel, Gül
AU  - Küçükali Türkyılmaz, Ayşegül
AU  - Kırbaş, Aynur
AU  - Bilgin Topaloğlu, Hacer
AU  - Serdaroğlu Beyazal, Münevver
AU  - Yıldırım, Murat
PY  - 2025
DA  - May
Y2  - 2025
DO  - 10.37990/medr.1629318
JF  - Medical Records
JO  - Med Records
PB  - Tıbbi Kayıtlar Derneği
WT  - DergiPark
SN  - 2687-4555
SP  - 370
EP  - 376
VL  - 7
IS  - 2
LA  - en
AB  - Aim: Our aim in this study was to demonstrate that rheumatoid arthritis (RA) patients have an increase in serum tryptase concentrations and that this correlates with the level of disease activity.Material and Method: The research involved 43 patients RA and 37 healthy participants as the control group. The average ages of the patients and the control group were 52.53±11.10 and 48.41±12.79 years, respectively. Sociodemographic information of all participants was recorded. Disease Activity Score 28 (DAS28), Health Assessment Questionnaire (HAQ) and Visual Analog Scale (VAS) scores were calculated after detailed examination to determine disease activity. Total serum tryptase concentrations were evaluated using enzyme-linked immunosorbent assay (ELISA).Results: Serum tryptase levels were higher in the RA group compared to the healthy group and a statistically significant difference was found (p
KW  - Biomarker
KW  - diagnosing
KW  - rheumatoid arthritis
KW  - serum tryptase
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UR  - https://doi.org/10.37990/medr.1629318
L1  - https://dergipark.org.tr/tr/download/article-file/4562482
ER  -