TY  - JOUR
T1  - A rare diagnosis in a child presenting with urinary incontinence: spinal ependymoma
TT  - Üriner inkontinans ile başvuran çocukta nadir bir tanı: Spinal ependimom
AU  - Terzi, Hatice Zeynep
AU  - Güneylioğlu, Muhammed Mustafa
AU  - Bilen, İnci Pınar
AU  - Pehlivan, Tayfun
AU  - Baykal, Duygu
AU  - Tutanç, Murat
PY  - 2025
DA  - August
Y2  - 2025
DO  - 10.70852/tmj.1642164
JF  - Turkish Medical Journal
JO  - TMJ
PB  - Ankara Yıldırım Beyazıt Üniversitesi Yenimahalle Eğitim ve Araştırma Hastanesi
WT  - DergiPark
SN  - 3023-8196
SP  - 124
EP  - 128
VL  - 10
IS  - 3
LA  - en
AB  - Patients presenting with various symptoms to the pediatric emergency department may be diagnosed with a spinal mass. Spinal ependymoma is a central nervous system tumor that is quite rare in childhood. Early diagnosis is important in terms of reducing morbidity and mortality. The presenting symptoms should be well understood, and necessary tests for differential diagnosis should be conducted. In this case, a 9-year-old male patient who presented to our emergency department with complaints of urinary incontinence and walking difficulties and was diagnosed with spinal ependymoma will be discussed.
KW  - Ataxia
KW  - Ependymoma
KW  - Spinal mass
KW  - Urinary incontinence
N2  - Çocuk acil servisine çeşitli semptomlarla başvuran hastalar spinal kitle tanısı alabilmektedir. Spinal ependimom, çocukluk çağında oldukça nadir görülen merkezi sinir sistemi tümörüdür. Erken tanı konulması morbidite ve mortalitenin azaltılması açısından önemlidir. Başvuru semptomları iyi bilinmeli ve ayırıcı tanıya yönelik gerekli tetkikler yapılmalıdır. Bu vakada, acil servisimize idrar kaçırma ve yürüme bozukluğu şikayetleri ile başvuran ve spinal ependimom tanısı alan 9 yaşındaki erkek hastadan bahsedilecektir.
CR  - Bach, F., Larsen, B. H., Rohde, K., Børgesen, S. E., Gjerris, F., Bøge-Rasmussen, T., Agerlin, N., Rasmusson, B., Stjernholm, P., & Sørensen, P. S. (1990). Metastatic spinal cord compression. Occurrence, symptoms,clinical presentations and prognosis in 398 patients with spinal cord compression. Acta neurochirurgica, 107(1-2), 37–43. https://doi.org/10.1007/BF01402610
CR  - Benesch, M., Weber-Mzell, D., Gerber, N. U., von Hoff, K., Deinlein, F., Krauss, J., Warmuth-Metz,M., Kortmann, R. D., Pietsch, T., Driever, P. H., Quehenberger, F., & Urban, C. (2010). Ependymoma of the spinal cord in children and adolescents: A retrospective series from the HIT database. Journal of Neurosurgery: Pediatrics, 6(2), 137–144. https://doi.org/10.3171/2010.5.PEDS09553
CR  - Dixit, K. S., & Kumthekar, P. U. (2020). Optimal Management of Corticosteroids in Patients with Intracranial Malignancies. Current Treatment Options in Oncology, 21(9), 77. https://doi.org/10.1007/s11864-020-00771-7
CR  - Ekuma, E. M., Ito, K., Chiba, A., Hara, Y., Kanaya, K., Horiuchi, T., Ohaegbulam, S., & Hongo, K. (2017). A Rare Case of Pediatric Lumbar Spinal Ependymoma Mimicking Meningitis. World neurosurgery, 100, 710. e1–e5. https://doi.org/10.1016/j.wneu.2017.02.016
CR  - Farzan, A., Ahmadi, P., Tasdighi, E., Zinatzadeh, M. R., & Pourbakhtyaran, E. (2022). Primary spinal tumors and masses in children. Iranian Journal of Child Neurology, 16(2), 129–135. https://doi.org/10.22037/ijcn.v16i2.30614
CR  - Godfraind, C., Kaczmarska, J. M., Kocak, M., Dalton, J., Wright, K. D., Sanford, R. A., Boop, F. A., Gajjar, A., Merchant, T. E., & Ellison, D. W. (2012). Distinct disease-risk groups in pediatric supratentorial and posterior fossa ependymomas. Acta neuropathologica, 124(2), 247–257. https://doi.org/10.1007/s00401-012-0981-9
CR  - Handbook of Clinical Neurology. (1997). Intrinsic spinal cord tumors (Vol. 24, p. 497). Elsevier. Hsu, W., & Jallo, G. I. (2013). Pediatric spinal tumors. Handbook of Clinical Neurology, 112, 959–965. https://doi.org/10.1016/B978-0-444-52910-7.00016-7
CR  - Khalid, S. I., Kelly, R., Adogwa, O., Carlton, A., Woodward, J., Ahmed, S., Khanna, R., Bagley, C., Cheng, J., Shah, S., & Mehta, A. I. (2018). Pediatric spinal ependymomas: An epidemiologic study. World Neurosurgery, 115, e119–e128. https://doi.org/10.1016/j.wneu.2018.03.206
CR  - Korshunov, A., Witt, H., Hielscher, T., Benner, A., Remke, M., Ryzhova, M., Milde, T., Bender, S., Wittmann, A., Schöttler, A., Kulozik, A. E., Witt, O., von Deimling, A., Lichter, P., & Pfister, S. (2010). Molecular staging of intracranial ependymoma in children and adults. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 28(19), 3182–3190. https://doi.org/10.1200/JCO.2009.27.3359
CR  - Kresbach, C., Neyazi, S., & Schüller, U. (2022). Updates in the classification of ependymal neoplasms: The 2021 WHO Classification and beyond. Brain Pathology, 32(4), e13068. https://doi.org/10.1111/bpa.13068
CR  - Louis, D. N., Perry, A., Wesseling, P., Brat, D. J., Cree, I. A., Figarella-Branger, D., Hawkins, C., Ng, H. K., Pfister, S. M., Reifenberger, G., Soffietti, R., von Deimling, A., & Ellison, D. W. (2021). The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro-oncology, 23(8), 1231–1251. https://doi.org/10.1093/neuonc/noab106
CR  - Martinez-Perez, R., et al. (2012). Acute neurological deterioration as a result of two synchronous hemorrhagic spinal ependymomas. Surgical Neurology International, 3, 33. https://doi.org/10.4103/2152-7806.93865
CR  - McGuire, C. S., Sainani, K. L., & Fisher, P. G. (2009). Incidence patterns for ependymoma: A surveillance, epidemiology, and end results study. Journal of Neurosurgery, 110(4), 725–729. https://doi.org/10.3171/2008.9.JNS08117
CR  - Merchant, T. E., Li, C., Xiong, X., Kun, L. E., Boop, F. A., & Sanford, R. A. (2009). Conformal radiotherapy after surgery for paediatric ependymoma: A prospective study. Lancet Oncology, 10, 258–266.
CR  - Pajtler, K. W., Witt, H., Sill, M., Jones, D. T., Hovestadt, V., Kratochwil, F., Wani, K., Tatevossian, R., Punchihewa, C., Johann, P., Reimand, J., Warnatz, H. J., Ryzhova, M., Mack, S., Ramaswamy, V., Capper, D., Schweizer, L., Sieber, L., Wittmann, A., Huang, Z., … Pfister, S. M. (2015). Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups. Cancer cell, 27(5), 728–743. https://doi.org/10.1016/j.ccell.2015.04.002
CR  - Parsa, A. T., Lee, J., Parney, I. F., Weinstein, P., McCormick, P. C., & Ames, C. (2004). Spinal cord and intradural-extraparenchymal spinal tumors: Current best practices and strategies. Journal of Neuro-oncology, 69, 291–311.
CR  - Rudà, R., Reifenberger, G., Frappaz, D., Pfister, S. M., Laprie, A., Santarius, T., Roth, P., Tonn, J. C., Soffietti, R., Weller, M., & Moyal, E. C. (2018). EANO guidelines for the diagnosis and treatment of ependymal tumors. Neuro-Oncology, 20(4), 445–456. https://doi.org/10.1093/neuonc/nox166
CR  - Sofuoğlu, Ö. E., & Abdallah, A. (2018). Pediatric spinal ependymomas. Medical Science Monitor, 24, 7072–7089. https://doi.org/10.12659/MSM.910447
CR  - Tihan, T., Zhou, T., Holmes, E., Burger, P. C., Ozuysal, S., & Rushing, E. J. (2008). The prognostic value of histological grading of posterior fossa ependymomas in children: a Children’s Oncology Group study and a review of prognostic factors. Modern Pathology, 21(2), 165–177. https://doi.org/10.1038/modpathol.3800999
UR  - https://doi.org/10.70852/tmj.1642164
L1  - https://dergipark.org.tr/tr/download/article-file/4619950
ER  -