TY - JOUR T1 - Prevalence of Infectious Diseases and the Assessment of Antibiotic Use in the Anesthesia Intensive Care Unit TT - Anestezi Yoğun Bakım Ünitesinde Enfeksiyöz Hastalıkların Prevalansı ve Antibiyotik Kullanımının Değerlendirilmesi AU - Kızılkale Kayıkcı, Gökçe AU - Aksun, Murat AU - Şencan, Atilla AU - Çakırgöz, Mensure AU - Girgin, Senem AU - Çetingöz, Esin PY - 2025 DA - August Y2 - 2025 DO - 10.32708/uutfd.1655566 JF - Journal of Uludağ University Medical Faculty JO - Uludağ Tıp Derg PB - Bursa Uludağ Üniversitesi WT - DergiPark SN - 1300-414X SP - 311 EP - 318 VL - 51 IS - 2 LA - en AB - Infections remain a major cause of morbidity and mortality in intensive care units. In this retrospective study, conducted to determine the prevalence of infections and resistance patterns in intensive care patients and to highlight the prognostic value of biomarkers and disease severity scores, 195 patients with suspected or confirmed infections admitted to the Anesthesia ICU of XXXXX Hospital between March 2020 and March 2021 were evaluated. Demographic data, infection foci, microbiological findings, biomarkers (WBC, CRP, PCT), and disease severity scores (APACHE II, SAPS II, SOFA) were analyzed. The infection prevalence was 60.6%, and ICU mortality was 49.7%. The median age was 67 years (IQR: 56–77), and 61% were male. Age, sex, and BMI were not associated with mortality. Non-survivors had significantly higher severity scores (APACHE II: 28.6 vs. 18.1; SAPS II: 63.2 vs. 41.2; SOFA: 10.8 vs. 6.4; all p KW - ICU infections KW - antimicrobial resistance KW - biomarkers KW - empirical antibiotics KW - mortality N2 - Enfeksiyonlar, yoğun bakım ünitelerinde morbidite ve mortalitenin başlıca nedenlerindendir. Yoğun bakım hastalarında enfeksiyonların yaygınlığını ve direnç paternlerini ortaya çıkararak, biyobelirteçler ile hastalık şiddeti skorlarının prognozdaki önemini vurgulamayı amaçladığımız bu retrospektif çalışmada; Mart 2020–Mart 2021 tarihleri arasında XXXXX Hastanesi Anestezi YBÜ’nde şüpheli veya doğrulanmış enfeksiyon tanısı ile izlenen 195 hasta değerlendirildi. Demografik veriler, enfeksiyon odakları, mikrobiyolojik bulgular, biyobelirteçler (WBC, CRP, PCT) ve hastalık şiddeti skorları (APACHE II, SAPS II, SOFA) analiz edildi. Enfeksiyon prevalansı %60,6; mortalite oranı %49,7 olarak bulundu. 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