TY - JOUR T1 - NT-proBNP levels in nephropathy cases with and without diabetes, echocardiographic abnormality, and hypertension AU - Güneş, Müslüm AU - Kadiroğlu, Ali Kemal PY - 2025 DA - March Y2 - 2025 DO - 10.5798/dicletip.1657530 JF - Dicle Medical Journal JO - diclemedj PB - Dicle Üniversitesi WT - DergiPark SN - 1300-2945 SP - 79 EP - 85 VL - 52 IS - 1 LA - en AB - Objective: Increased NT-proBNP level is a diagnostic sign for heart failure and is associated with cardiovascular mortality. It is related to chronic kidney disease (CKD) in also cases without heart failure. In this study, the authors aimed to investigate NT-proBNP levels in CKD cases with and without diabetes, echocardiographic abnormality, and hypertension.Methods: Sixty-four cases (26 diabetic and 38 non-diabetic) with stage 3-4 CKD were investigated in the study. Blood pressure values were measured on the right arm after resting for at least 5 minutes. M-mode two-dimensional echocardiography device and ultrasonography were used to evaluate cardiac and renal findings. Blood samples were taken for biochemical, hematological, hormonal and serological parameters of the patients after 12 hours of fasting. Nt-proBNP levels were measured by Elecys ProBNP sandwich immunoassay method in the Biochemistry laboratory.Results: NT-proBNP levels were not statistically different according to the presence and absence of diabetes (p=0.821) in CKD cases. However, stage-4 CKD had significantly higher NT-proBNP level than stage-3 CKD in both diabetic (p KW - NT-proBNP KW - kidney disease KW - diabetes mellitus KW - echocardiography CR - 1.Yang P, Rooney MR, Wallace AS, et al. Associationsbetween diet quality and NT-proBNP in U.S. adults,NHANES 1999-2004. Am J Prev Cardiol 2023; 16:100528. CR - 2.Lu Y, Chen J, Su L, et al. 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