TY - JOUR T1 - Investigation of the Relationship Between Stroke and STEMI in Young and Middle-Aged Patients and COVID-19 TT - Stroke ve STEMI Tanılı Genç ve Orta Yaşlı Hastaların COVID-19 ile İlişkisinin Araştırılması AU - Yılmaz Dursun, Gözde AU - Baykan, Necmi AU - Yıldırım, Haticenur AU - Aytekin Akdağ, Rukiye AU - Toker, İbrahim PY - 2025 DA - August Y2 - 2025 JF - Journal of Anatolian Medical Research JO - JAMER PB - Kayseri Şehir Eğitim ve Araştırma Hastanesi WT - DergiPark SN - 2587-1153 SP - 28 EP - 32 VL - 10 IS - 2 LA - en AB - Aim: In this study, we aimed to elucidate the potential relationship between the COVID-19 pandemic and theincreasing occurrence of stroke and ST-segment elevation myocardial infarction (STEMI) in younger individuals, aswe have been encountering a growing number of such cases in routine clinical practice.Materials and Methods: This study was conducted on patients aged 50 years or younger who presented to our clinicbetween January 1, 2024, and December 31, 2024, and were diagnosed with STEMI or stroke. The history of priorCOVID-19 infection was evaluated retrospectively. Patients who had a positive Polymerase Chain Reaction (PCR)test or had been clinically and radiologically diagnosed with COVID-19 and received treatment were classifiedas having a history of COVID-19 positivity (Group I). Patients who did not meet either of these two criteria wereclassified as having no history of COVID-19 (Group II).Results: A total of 196 patients aged 50 years or younger who were diagnosed with either infarction STEMI orischemic stroke were included in the study. Patients were classified into two groups based on their history ofCOVID-19 infection: Group I (COVID-19 positive) and Group II (COVID-19 negative). The distribution of diagnosesbetween the two groups revealed a statistically significant difference between the rates of ischemic stroke andSTEMI (p=0.026). Specifically, a higher proportion of patients diagnosed with ischemic stroke were found to have ahistory of PCR-confirmed COVID-19 infection.Conclusion: This study highlights the importance of considering not only the acute effects of the COVID-19pandemic but also its potential to increase the risk of stroke in the long term, emphasizing the need for attention toits prolonged impact. KW - COVID-19 KW - STEMI KW - Stroke N2 - Amaç: Bu çalışmada, rutin klinik pratikte giderek artan sayıda inme ve ST-segment yükselmeli miyokard enfarktüsü(STEMI) vakasıyla karşılaştığımız genç bireylerde COVID-19 pandemisi ile inme ve ST-segment yükselmeli miyokardenfarktüsü görülme sıklığındaki artış arasındaki olası ilişkiyi aydınlatmayı amaçladık.Gereç ve Yöntemler: Bu çalışma, 01.01.2024 ile 31.12.2024 tarihleri arasında kliniğimize başvuran ve 50 yaş ve altındaolan, ST segment elevasyonlu miyokard enfarktüsü veya inme tanısı almış hastalar üzerinde gerçekleştirilmiştir.Hastaların özgeçmişlerinde COVID-19 geçirmiş olma durumları retrospektif olarak değerlendirilmiştir. Dahiledilen hastalardan, Polimeraz Zincir Reaksiyon (PCR) testi pozitif olanlar ya da klinik ve radyolojik bulgularlaCOVID-19 tanısı alarak tedavi görmüş olanlar “özgeçmişinde COVID-19 pozitif” (Grup I) olarak kabul edilmiştir.Bu iki kriterden herhangi birini karşılamayan hastalar ise “özgeçmişinde COVID-19 negatif” (Grup II) olaraksınıflandırılmıştır.Bulgular: Çalışmaya, 50 yaş ve altı olup iskemik inme veya ST segment elevasyonlu miyokard enfarktüsü (STEMI)tanısı alan toplam 196 hasta dahil edildi. Hastalar, COVID-19 geçirme öyküsüne göre iki gruba ayrıldı: Grup I(COVID-19 pozitif) ve Grup II (COVID-19 negatif). Tanı dağılımı değerlendirildiğinde, gruplar arasında iskemikinme ve STEMI sıklığı açısından istatistiksel olarak anlamlı bir fark saptandı (p=0,026). Özellikle, iskemik inmetanısı alan hastalarda PCR ile doğrulanmış COVID-19 öyküsünün daha yüksek oranda bulunduğu gözlendi.Sonuç: Bu çalışmayla COVID-19 pandemisinin sadece akut zararlarına değil sonrasında inme olasılığını arttırmadurumu da göz önüne alınarak uzun dönemdeki etkilerine dikkat edilmesi gerektiği sonucuna varıldı. CR - 1. Alpaslan M, Baykan N, Oktay M, Salt Ö, Koyuncu S, Bol O, et al. Evaluation of patients diagnosed with thromboembolism in the emergency department before and during the COVID-19 pandemic. Med Res Arch. 2024;12(10). CR - 2. Mehta S, Kakouros N, Mir T, Loree S, Qureshi W. Prevalence and Outcomes of Patients With Acute Ischemic Stroke With Concomitant ST-Segment–Elevation Myocardial Infarction (Results From National Inpatient Sample 2016–2019). Stroke. 2024;55(5):1245-1253. CR - 3. Partow-Navid R, Prasitlumkum N, Mukherjee A, Varadarajan P, Pai RG. Management of ST elevation myocardial infarction (STEMI) in different settings. 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UR - https://dergipark.org.tr/tr/pub/jamer/issue//1665777 L1 - https://dergipark.org.tr/tr/download/article-file/4726316 ER -