TY - JOUR T1 - Radical Surgery with a Multidisciplinary Approach in a Case of Radiation Induced Rhabdomyosarcoma of Breast Invading the Chest Wall, Lung and Heart AU - Şenol, Kazım AU - Polatkan, Seyit Ali Volkan AU - Acar, İrem Zehra AU - Çeçen, Süleyman AU - Özşen, Mine AU - Evrensel, Türkkan PY - 2022 DA - December DO - 10.58241/ksbd.3 JF - Kapadokya Sağlık Bilimleri Dergisi JO - KSBDER PB - Kapadokya Üniversitesi WT - DergiPark SN - 2979-9880 SP - 25 EP - 30 VL - 1 IS - 1 LA - en AB - Abstract Sarcoma of the breast is usually seen following radiation therapy. Radiation-induced sarcoma treatment modalities include chemotherapy, radiotherapy and surgery. Even conservative treatment can achieve treatment response, locally advanced tumors should be removed with negative surgical margins. Unfortunately, the literaturelacksofprospective data regarding the disease rarity. Clinicians should seek for individualised treatment options considered in multidisciplinary tumor boards. Here we present a radiation-induced chemotherapy resistant breast sarcoma patient successfully managed with en-bloc radical surgical removal and reconstruction under the provision multidisciplinary team. KW - Breast Cancer KW - Breast Sarcoma KW - Radiation-Induced Sarcoma KW - Surgery CR - Brady, M. S., Gaynor, J. J., andBrennan, M. F. (1992). Radiation-associated sarcoma of bone and soft tissue. Arch Surg, 127 (12), 1379-1385. https://doi.org/10.1001/archsurg.1992.01420120013002 CR - Cha, C., Antonescu, C. R., Quan, M. L., Maru, S., andBrennan, M. F. (2004). Long-term results with resection of radiation-induced soft tissue sarcomas. Ann Surg, 239 (6), 903-910. https://doi.org/10.1097/01.sla.0000128686.51815.8b CR - Lagrange, J. L., Ramaioli, A., Chateau, M. C., Marchal, C., Resbeut, M., Richaud, P., Lagarde, P., Rambert, P., Tortechaux, J., Seng, S. H., de la Fontan, B., Reme-Saumon, M., Bof, J., Ghnassia, J. P., andCoindre, J. M. (2000). Sarcoma after radiation therapy: retrospective multiinstitutional study of 80 histologically confirmed cases. Radiation Therapist and Pathologist Groups of the Fédération Nationale des Centres de Lutte Contre le Cancer. Radiology, 216 (1), 197-205. https://doi.org/10.1148/radiology.216.1.r00jl02197 CR - Riad, S., Biau, D., Holt, G. E., Werier, J., Turcotte, R. E., Ferguson, P. C., Griffin, A. M., Dickie, C. I., Chung, P. W., Catton, C. N., O'Sullivan, B., andWunder, J. S. (2012). The clinical and functional outcome for patients with radiation-induced soft tissue sarcoma. Cancer, 118(10), 2682-2692. https://doi.org/10.1002/cncr.26543 CR - Russell, W. O., Cohen, J., Enzinger, F., Hajdu, S. I., Heise, H., Martin, R. G., Meissner, W., Miller, W. T., Schmitz, R. L., andSuit, H. D. (1977). A clinical and pathological staging system for soft tissue sarcomas. Cancer, 40(4),1562-1570. https://doi.org/10.1002/1097-0142(197710)40:4 CR - Sheth, G. R., Cranmer, L. D., Smith, B. D., Grasso-Lebeau, L., andLang, J. E. (2012). Radiation-induced sarcoma of the breast: a systematic review. Oncologist, 17(3),405-418. https://doi.org/10.1634/theoncologist.2011-0282 UR - https://doi.org/10.58241/ksbd.3 L1 - https://dergipark.org.tr/tr/download/article-file/4789110 ER -