@article{article_1689160, title={Impact of Intraoperative End-Tidal CO₂ Variations on Postoperative Nausea, Vomiting, and Pain}, journal={Journal of Cukurova Anesthesia and Surgical Sciences}, volume={8}, pages={181–184}, year={2025}, DOI={10.36516/jocass.1689160}, author={Özgüner, Yusuf and Güzelkaya, Derya and Çataroğlu, Cem Koray and Erdem Hıdıroğlu, Ela and Altınsoy, Savaş and Ergil, Julide}, keywords={End-tidal karbondioksit, Ağrı, Postoperatif bulantı ve kusma, Robotik yardımlı laparoskopik radikal prostatektomi}, abstract={Aim: Patients undergoing robotic-assisted laparoscopic procedures tend to experience a higher frequency of postoperative nausea and vomiting (PONV). This study aimed explore the influence of intraoperative end-tidal carbon dioxide (ETCO₂) levels on the occurrence of PONV in robotic surgery. Methods: This observational clinical study included patients undergoing robotic laparoscopic radical prostatectomy. Patients were divided into two groups based on intraoperative ETCO₂ levels: Group 1 (26–35 mmHg) and Group 2 (36–45 mmHg). The incidence of PONV, the use of rescue antiemetics, and pain scores were recorded at 0, 2, 4, 8, 12, and 24 hours postoperatively. Results: We found that Group 1 exhibited lower Apfel scores at both 0 (p < 0.001) and 2 (p = 0.046) hours post-surgery. Furthermore, Group 2 had a higher incidence of PONV and greater usage of rescue antiemetics within the first 24 hours following surgery. (p <0.05) Conclusion: We found that lower intraoperative ETCO₂ levels were associated with a reduced incidence of PONV in robotic laparoscopic surgery, a procedure known to carry a high risk of PONV.PONV remains a significant clinical issue that negatively affects patient comfort and recovery. we believe that future research should continue to explore the effectiveness of both pharmacological and non-pharmacological approaches for the prevention of PONV.}, number={2}, publisher={Merthan TUNAY}