@article{article_1689237, title={First Fatal Human Case of Beta-Cyfluthrin Intoxication in Türkiye: A Case Report}, journal={Journal of Emergency Medicine Case Reports}, volume={16}, pages={89–91}, year={2025}, DOI={10.33706/jemcr.1689237}, author={Golcuk, Yalcin and Aksakal, Ahmet and Karakoyun, Ömer Faruk and Yıldız Kaya, Şule}, keywords={Cyfluthrin, İnsektisitler, Pestisit Zehirlenmesi, Multiorgan Yetmezliği, Kırsal Nüfus}, abstract={Introduction Cyfluthrin, a type II synthetic pyrethroid, is extensively used in agricultural and veterinary practices. While generally considered to have low mammalian toxicity, significant exposure to concentrated formulations can lead to systemic toxicity and multiorgan failure. Human fatalities due to cyfluthrin are rare and not well-characterized in the literature. Case Report We report the case of a 67-year-old female shepherd with no known comorbidities who presented to the emergency department approximately 24 hours after dermal and possible inhalational exposure to a veterinary insecticide containing 25 g/L beta-cyfluthrin in emulsifiable concentrate form. She had applied the formulation directly to livestock without protective equipment. Within hours, she developed acute retrosternal chest pain, vomiting, and transient loss of consciousness. Upon arrival to the emergency department, she was hypotensive, bradycardic, and hypoxic. Laboratory analysis revealed severe metabolic acidosis, hyperglycemia, markedly elevated hepatic and cardiac enzymes, acute kidney injury, and coagulopathy. Imaging showed a moderate pericardial effusion without tamponade. Despite intensive supportive care, including high-dose sodium bicarbonate, N-acetylcysteine, and fluid resuscitation, her condition deteriorated, culminating in disseminated intravascular coagulation, shock, and death on ICU day 8. Conclusion This case illustrates the potential lethality of beta-cyfluthrin exposure in humans and underscores the importance of early recognition, protective practices, and aggressive management in suspected pyrethroid poisoning.}, number={3}, publisher={Acil Tıp Uzmanları Derneği}