TY  - JOUR
T1  - Mad Honey and Its Possible Biological Mechanisms in Alleviating Chronic Obstructive Pulmonary Disease (COPD)
TT  - Deli Bal ve Kronik Obstrüktif Akciğer Hastalığı (KOAH)’nı yatıştırmada yardımcı olabilecek potansiyel mekanizmaları.
AU  - Aydın, Özge Zelal
AU  - Akbay, Ayşegül
PY  - 2025
DA  - September
Y2  - 2025
JF  - Yüksek İhtisas Üniversitesi Sağlık Bilimleri Dergisi
JO  - YIU Saglik Bil Derg
PB  - Yüksek İhtisas Üniversitesi
WT  - DergiPark
SN  - 2717-8439
SP  - 55
EP  - 58
VL  - 6
IS  - 2
LA  - en
AB  - Introduction: Chronic Obstructive Pulmonary Disease is a progressive respiratory condition characterized by airflow limitation, chronic inflammation, and structural damage in the lungs The disease is primarily caused by long-term exposure to irritants, particularly cigarette smoke and, leading to airway remodeling, fibrosis, and oxidative stress. Although, current treatments help manage symptoms, they do not offer a definitive cure, and the morbidity and mortality rates are still high with very significant healthcare costs. Therefore, there is growing interest in alternative and natural remedies that may complement conventional therapies. One such substance is mad honey a rare and potent type of honey derived from the nectar of Rhododendron species, particularly Rhododendron ponticum and Rhododendron luteum.Conclusion: In this commentary, we explore the possible mechanisms, by which mad honey could alleviate Chronic Obstructive Pulmonary Disease symptoms and improve lung function,considering different molecular and biological aspects.
KW  - COPD
KW  - mad honey
KW  - rhododendron
KW  - inflammation
N2  - Giriş: Kronik Obstrüktif Akciğer Hastalığı nefes darlığı, kronik enflamasyon ve akciğerlerde yapısal hasar ile kendini gösteren ilerleyici bir hastalıktır. Hastalığa, hava yolu yeniden şekillenmesi, fibröz ve oksidatif strese yol açan, özellikle sigara dumanı ve çevresel kirleticiler gibi irritan maddelere uzun-süreli maruziyet sebep olmaktadır. Güncel tedaviler semptomları yönetmeye yardımcı olsa da kesin bir tedavi sağlamamakta ve çok ciddi sağlık masraflarıyla birlikte, morbidite ve mortalite oranları hâlâ oldukça yüksek seyretmektedir. Bu sebepten, güncel tedavilere eşlik eden alternatif ve doğal tedavilere olan ilgi her geçen gün artmaktadır. Bunlara örnek olarak ender bulunan ve Rhododendron türlerinden, özellikle Rhododendron ponticum ve Rhododendron luteum, elde edilen ‘Deli Bal’ verilebilir.Sonuç: Bu tartışmada, Deli Bal’ın Kronik Obstrüktif Akciğer Hastalığı semptomlarını yatıştırma ve akciğer fonksiyonlarını geliştirmede yardımcı olma potansiyeli taşıyan mekanizmalar, farklı moleküler ve biyolojik mekanizmalar göz önünde bulundurularak incelenmiştir.
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UR  - https://dergipark.org.tr/tr/pub/yuksekihtisas/issue//1692061
L1  - https://dergipark.org.tr/tr/download/article-file/4839082
ER  -