TY - JOUR T1 - Thyroid Papillary Carcinoma with Sternum Metastasis: A Case Report TT - Sternum Metastazı Olan Tiroid Papiller Karsinomu: Bir Olgu Sunumu AU - Esmez, Omer AU - Deniz, Gulnihal AU - Yildiz Esmez, Merve PY - 2025 DA - August Y2 - 2025 DO - 10.56941/odutip.1715906 JF - ODÜ Tıp Dergisi JO - ODU Tıp Derg PB - Ordu Üniversitesi WT - DergiPark SN - 2148-6816 SP - 75 EP - 81 VL - 12 IS - 2 LA - en AB - Papillary thyroid carcinoma (PTC) is generally an indolent malignancy with excellent prognosis; however, distant metastasis occurs in approximately 10% of cases, predominantly to the lungs and bones. We report the case of a 56-year-old male diagnosed with papillary thyroid carcinoma exhibiting sternal metastasis, a rare site of distant spread. After initial surgical management with total thyroidectomy, imaging and histopathological evaluation confirmed metastatic involvement of the sternum. This report emphasizes the diagnostic approach, treatment considerations, and the importance of a multidisciplinary strategy in managing rare metastatic patterns of thyroid carcinoma. KW - papillary thyroid carcinoma KW - distant metastasis KW - sternum metastasis KW - total thyroidectomy KW - nuclear medicine. N2 - Papiller tiroid karsinomu (PTC) genellikle mükemmel prognoza sahip yavaş ilerleyen bir malignitedir; ancak, vakaların yaklaşık %10'unda uzak metastaz görülür, çoğunlukla akciğerlere ve kemiklere. Sternal metastaz gösteren papiller tiroid karsinomu tanısı konulan 56 yaşında bir erkek hastayı bildiriyoruz, bu uzak yayılımın nadir bir yeridir. Total tiroidektomi ile ilk cerrahi tedaviden sonra, görüntüleme ve histopatolojik değerlendirme sternumun metastatik tutulumunu doğruladı. Bu rapor, nadir görülen metastatik tiroid karsinom modellerinin yönetiminde tanı yaklaşımını, tedavi hususlarını ve multidisipliner bir stratejinin önemini vurgulamaktadır. CR - Batta R, Njoum Y, Deek R, Awad F, Bakri IA, Maree M: Follicular thyroid carcinoma with sternal metastasis: A case report. International Journal of Surgery Case Reports 2023, 109:108625. CR - Paspala A, Papakonstantinou D, Pikoulis E, Tomos P, Nastos C, Nastos K: Synchronous sternal metastasectomy and total thyroidectomy for differentiated thyroid cancer: a rare case report. Cureus 2022, 14(11). CR - Adil A, Abdelfetah Z, Khalid T, Abderahman K, Issam R, Yacine M: Isolated Sternal Metastasis Arising from Well Diferencied Thyroid Carcinoma. American Journal of Thoracic and Cardiovascular Surgery 2017, 2(1):7-9. CR - Lam, A. K. (2022). Papillary thyroid carcinoma: current position in epidemiology, genomics, and classification. In Papillary Thyroid Carcinoma: Methods and Protocols (pp. 1-15). New York, NY: Springer US. CR - Pradeep S, Hedne N, Vidhyadharan S, Rajiv S: Sternal metastatectomy in a case of papillary thyroid carcinoma. BMJ Case Reports CP 2020, 13(10):e235967. CR - Piñar-Gutiérrez A, Romero-Lluch AR, Dueñas-Disotuar S, de Lara-Rodríguez I, Gálvez-Moreno MÁ, Martín-Hernández T, García-Alemán J, Martínez-de Pinillos G, Navarro-González E: Bone metastases from differentiated thyroid cancer: characteristics and prognostic factors in a multicenter series. European Thyroid Journal 2023, 12(5). CR - Kapustin DA, Yun J, Su V, Rubin SJ, Nicastri DG, Flores RM, Urken ML: Subtotal Sternectomy with Reconstruction for Metastatic Thyroid Carcinoma. VideoEndocrinology™ 2023, 10(3):46-48. CR - Dueñas-Disotuar S, Piñar-Gutiérrez A, de Lara-Rodríguez I, Sastre-Marcos J, Anda-Apiñániz E, Oleaga-Alday A, Galofré-Ferrater JC, Orois-Añon A, Alcázar-Lázaro V, Martínez-Guasch L: Bone metastasis in differentiated thyroid cancer: Spanish multicenter study of clinical characteristics, survival and prognostic factors. Frontiers in Endocrinology 2024, 15:1466245. CR - Pompeu YA: Bone Metastases in Differentiated Thyroid Carcinoma: Resection Strategy and Other Prognostic Factors: Harvard University; 2018. CR - Khired ZA, Hussein MH, Jishu JA, Toreih AA, Shaalan AA, Ismail MM, Fawzy MS, Toraih EA: Osseous metastases in thyroid cancer: unveiling risk factors, disease outcomes, and treatment impact. Cancers 2023, 15(14):3557. CR - Murakawa T, Nakajima J, Tanaka M, Matsumoto J, Takeuchi E, Takamoto S, Sugasawa T, Mibu K: Metastatic sternal tumor from thyroid papillary carcinoma; report of a case. Kyobu geka The Japanese Journal of Thoracic Surgery 2002, 55(13):1161-1166. CR - Ouakrim H, Dafali Nei, Rafi S, El Mghari G, El Ansari N: Sternal Metastasis in Follicular Thyroid Carcinoma: An Atypical Presentation. 2023. CR - Syazni MA, Gendeh HS, Kosai NR, Ramzisham A, Gendeh BS, Basiron N, Imran FH: Follicular thyroid cancer with sternal metastasis-challenges and outcomes. Med J Malaysia 2017, 72(1):80-82. UR - https://doi.org/10.56941/odutip.1715906 L1 - https://dergipark.org.tr/tr/download/article-file/4942716 ER -