TY  - JOUR
T1  - Time-Dependent Effects of Normothermic and Mild Hypothermic Cardiopulmonary Bypass on the De Ritis Ratio
TT  - Normotermik ve Hafif Hipotermik Kardiyopulmoner Bypass'ın De Ritis Oranı Üzerindeki Zamana Bağlı Etkileri
AU  - Dikme, Reşat
PY  - 2025
DA  - September
Y2  - 2025
DO  - 10.36516/jocass.1745062
JF  - Journal of Cukurova Anesthesia and Surgical Sciences
JO  - J Cukurova Anesth Surg
PB  - Merthan TUNAY
WT  - DergiPark
SN  - 2667-498X
SP  - 265
EP  - 270
VL  - 8
IS  - 3
LA  - en
AB  - Aim: This study aims to comparatively evaluate the effects of normothermic and mild hypothermic cardiopulmonary bypass (CPB) strategies on liver function in coronary artery bypass grafting (CABG) operations through the dynamics of the De Ritis ratio.Methods: This retrospective study included 150 patients who underwent CABG with either normothermic (35–37 °C, n=75) or mild hypothermic (28–34 °C, n=75) CPB. Liver function parameters (AST, ALT, De Ritis ratio, GGT, bilirubin) were assessed at the prebypass, postbypass, and postoperative time points. Statistical analysis was performed using SPSS software, with significance set at p
KW  - Cardiopulmonary bypass
KW  - Normothermia
KW  - Hypothermia
KW  - De Ritis ratio
KW  - AST/ALT
KW  - Hepatic injury
N2  - Amaç: Bu çalışma, koroner arter bypass greftleme (KABG) operasyonlarında normotermik ve hafif hipotermik kardiyopulmoner bypass (KPB) stratejilerinin karaciğer fonksiyonu üzerindeki etkilerini De Ritis oranının dinamikleri üzerinden karşılaştırmalı olarak değerlendirmeyi amaçlamaktadır.Yöntem: Retrospektif olarak tasarlanan bu çalışmaya, normotermik (35–37 °C, n=75) veya hafif hipotermik (28–34 °C, n=75) KPB altında KABG uygulanan toplam 150 hasta dâhil edilmiştir. Karaciğer fonksiyon parametreleri [AST, ALT, De Ritis oranı (AST/ALT), GGT ve bilirubin] prebypass, postbypass ve postoperatif dönemlerde değerlendirilmiştir. İstatistiksel analizler SPSS yazılımı kullanılarak gerçekleştirilmiş ve anlamlılık düzeyi p
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UR  - https://doi.org/10.36516/jocass.1745062
L1  - https://dergipark.org.tr/tr/download/article-file/5065653
ER  -