@article{article_1746396, title={Prognostic value of left ventricular remodelling phenotypes in patients undergoing transcatheter aortic valve implantation}, journal={Journal of Health Sciences and Medicine}, volume={8}, pages={839–846}, year={2025}, DOI={10.32322/jhsm.1746396}, author={Güney, Murat Can}, keywords={Transkateter aort kapak implantasyonu, Sol ventrikül yeniden şekillenme, Konsantrik hipertrofi, Eksantrik hipertrofi, Ekokardiyografi, Ters yeniden şekillenme, Kalıcı pacemaker, Aort darlığı}, abstract={Aims: This study aimed to evaluate the impact of baseline left ventricular (LV) remodeling phenotypes on clinical and echocardiographic outcomes in patients undergoing transcatheter aortic valve implantation (TAVI). Methods: A total of 413 patients with aortic stenosis (AS) who underwent TAVI between July 2011 and January 2024 were retrospectively analyzed. Based on echocardiographic parameters, patients were classified into concentric remodeling (CR, 7%), concentric hypertrophy (CH, 84.5%), and eccentric hypertrophy (EH, 8.5%) groups. Results: Patients in the EH group were significantly younger (mean age: 76, p <0.001) and predominantly male (p <0.001). Prior myocardial infarction (MI) (p <0.001) and coronary artery bypass grefting (CABG) (p=0.003) were more common in this group. EH patients had the lowest baseline ejection fraction (EF) (p <0.001), highest left ventricular end diastolic dimension (LVEDD) and left ventricular end systolic dimension (LVESD) (both p <0.001), increased prevalence of low flow low gradient (LFLG) AS (p <0.001), and lower frequency of very severe aortic stenosis (VSAS) (p=0.005). At one-year follow-up, EH patients showed the most pronounced improvement in EF (+17.6%, p=0.002) and reduction in LVEDD (-7.3%, p=0.006). Permanent pacemaker implantation was highest in the EH group (28.6%) and significantly greater than in the CH group (p=0.022). No significant differences in in-hospital or one-year mortality were observed between groups (p>0.05). Conclusion: LV remodeling patterns are strongly associated with reverse remodeling and conduction-related complications after TAVI. While EH patients show greater structural recovery, they are also at higher risk for post-procedural pacemaker implantation.}, number={5}, publisher={MediHealth Academy Yayıncılık}