@article{article_1752156, title={Comparison of thoracic epidural and peripheral regional analgesia techniques for postoperative pain management in video-assisted thoracoscopic surgery (VATS) procedures: a retrospective study}, journal={Anatolian Current Medical Journal}, volume={7}, pages={583–588}, year={2025}, DOI={10.38053/acmj.1752156}, author={Mendes, Ergun and Yaylak, Doruk and Sincer, Yasemin and Manici, Mete and Gürkan, Yavuz}, keywords={Torakal epidural analjezi, video yardımlı torakoskopik cerrahi, paravertebral blok, erector spinae plan blok, serratus anterior plan blok, postoperatif ağrı}, abstract={Aims: Effective postoperative analgesia is essential in thoracic surgery to preserve respiratory function, facilitate early mobilization, and reduce pulmonary complications. Thoracic epidural analgesia (TEA) has traditionally been regarded as the gold standard for pain control. However, the increasing use of minimally invasive approaches such as video-assisted thoracoscopic surgery (VATS) has prompted the adoption of ultrasound-guided peripheral regional anesthesia techniques, including the paravertebral block (PVB), erector spinae plane block (ESPB), and serratus anterior plane block (SAPB). This study aimed to compare TEA and peripheral regional blocks in terms of postoperative pain scores, opioid consumption, and recovery parameters in patients undergoing VATS procedures. Methods: This retrospective study included patients who underwent elective VATS between January 2023 and January 2025. Based on the analgesic technique received, patients were divided into two groups: TEA (n=82) and peripheral block group (PER, n=65). Pain was assessed using the Visual Analog Scale (VAS) at the post-anesthesia care unit (PACU) and at 24, 48, and 72 hours postoperatively. Opioid doses were standardized to morphine milligram equivalents (MME). Additional outcomes included intraoperative opioid use, postoperative rescue analgesia, length of hospital stay (LOS), complication rates, and 90-day mortality. Results: Patients in the TEA group had significantly lower VAS scores at all time points compared to the PER group (p <0.001). PACU opioid administration and total MME consumption were also significantly reduced in the TEA group (0 mg [IQR 0–2] vs. 2 mg [IQR 0–4], p <0.001). Although intraoperative opioid use was generally similar, TEA provided greater opioid-sparing effects. No significant differences were observed between groups in LOS, complication rates, or 90-day mortality. Conclusion: TEA demonstrated superior efficacy in postoperative pain control and opioid reduction compared to peripheral regional anesthesia techniques in patients undergoing VATS. While TEA remains the preferred option when feasible, ultrasound guided peripheral blocks offer a valuable alternative, particularly in patients with contraindications to neuraxial techniques.}, number={5}, publisher={MediHealth Academy Yayıncılık}