@article{article_1752986, title={Clinical Features, Diagnosis, and Treatment Approaches in Granulomatous Mastitis: A Single-Center Alternative Treatment Experience}, journal={Osmangazi Tıp Dergisi}, volume={48}, pages={337–342}, year={2026}, DOI={10.20515/otd.1752986}, url={https://izlik.org/JA97NS94MN}, author={Yılmaz, Arda Şakir and Badak, Bartu and Ulfanov, Orkhan}, keywords={Granülomatöz mastit, seroma, vakum tedavisi, negatif basınç, segmental mastektomi}, abstract={Granulomatous mastitis (GM) is a rare, benign, but chronically progressive inflammatory breast disease. This study evaluated the effect of negative pressure vacuum therapy (NPVT) on postoperative seroma formation in GM. Twelve patients treated between May 2018 and July 2023 were retrospectively analyzed. Patients were divided into two groups: Group 1 underwent abscess drainage and biopsy followed by 48 hours of NPVT before segmental mastectomy, whereas Group 2 underwent drainage and mastectomy in the same session. Seroma formation was assessed by ultrasonography at 3 months. No significant differences were found between groups regarding age, comorbidities, or baseline demographics (p>0.05). Mean seroma size was 1.27 cm in Group 1 and 3.28 cm in Group 2, showing a statistically significant difference (p<0.001). NPVT significantly reduced seroma formation, enhanced tissue healing, and decreased complication rates. These findings suggest that NPVT may serve as an effective adjuvant method in the surgical management of GM. However, the small sample size and short follow-up period are study limitations, indicating the need for larger prospective studies to confirm these results.}, number={2}