TY - JOUR T1 - Canal of Nuck Cyst with Endometriosis Presenting as a Left Inguinal Mass: A Rare Clinical Variant TT - Endometriozis İçeren ve Sol İnguinal Kitle ile Prezente Olan Nuck Kanal Kisti: Nadir Bir Klinik Varyant AU - Akdemir, Celal AU - Özuyar Şimşek, Gülin AU - Çoban, Şimal AU - Güner, Murat AU - Sancı, Muzaffer PY - 2025 DA - September Y2 - 2025 JF - Journal of Cukurova Anesthesia and Surgical Sciences JO - J Cukurova Anesth Surg PB - Merthan TUNAY WT - DergiPark SN - 2667-498X SP - 333 EP - 335 VL - 8 IS - 3 LA - en AB - A cyst of the canal of Nuck is a rare clinical entity in females, resulting from the failure of obliteration of the processus vaginalis. Although it is typically diagnosed in the pediatric population, it is extremely rare in adult women and often misdiagnosed as an inguinal hernia, leading to delays in appropriate treatment. Clinically, it usually presents as a painless, fluctuating mass in the inguinal region. Ultrasonography is the primary imaging modality for diagnosis, while magnetic resonance imaging (MRI) can further delineate the origin and anatomical relationships of the lesion. Surgical excision remains the standard treatment approach.Herein, we present the case of a 34-year-old woman who presented with a painless swelling in the left inguinal region. A preoperative diagnosis was established based on imaging findings, and the lesion was surgically excised. Histopathological examination revealed a focus of endometriosis within the cyst wall. This case highlights the importance of considering rare coexisting pathologies such as endometriosis in the differential diagnosis of canal of Nuck cysts in adult women and aims to raise clinical awareness of this uncommon presentation. KW - Canal of Nuck cyst KW - Endometriosis KW - Inguinal mass KW - Female KW - Magnetic resonance imaging KW - Surgical excision N2 - Nuck kanal kisti, kadınlarda processus vaginalis’in obliterasyonunun gerçekleşmemesi sonucu gelişen nadir bir klinik tablodur. Genellikle pediatrik yaş grubunda tanı alan bu durum erişkin kadınlarda oldukça nadir görülür ve çoğu zaman inguinal herni ile karıştırılarak tanı gecikmelerine yol açar. Klinik olarak sıklıkla dalgalanan, ağrısız, inguinal bölgede kitle ile prezente olur. Tanıda ultrasonografi temel görüntüleme yöntemi olup, manyetik rezonans görüntüleme (MRG) ile lezyonun orijini ve komşuluk ilişkileri netleştirilebilir. Tedavide cerrahi eksizyon standart yaklaşımdır.Bu yazıda, sol inguinal bölgede ağrısız şişlik şikayeti ile başvuran, preoperatif görüntülemelerle tanısı konulan ve cerrahi olarak eksize edilen, histopatolojik incelemesinde kist duvarında endometriozis odağı saptanan 34 yaşında kadın olgu sunulmaktadır. Bu sunum, erişkin kadınlarda nadir görülen Nuck kanal kistlerinin ayırıcı tanısında endometriozis gibi eşlik edebilecek patolojilere dikkat çekmeyi ve klinik farkındalığı artırmayı amaçlamaktadır. CR - 1. Kohlhauser M, Pirsch JV, Maier T, Viertler C, Fegerl R. The cyst of the canal of Nuck: anatomy, diagnostic and treatment of a very rare diagnosis—a case report of an adult woman and narrative review of the literature. Medicina (Kaunas). 2022;58(10):1353. [Crossref] CR - 2. Prodromidou A, Paspala A, Schizas D, Spartalis E, Nastos C, Machairas N. Cyst of the canal of Nuck in adult females: a case report and systematic review. Biomed Rep. 2020;12(6):333–8. [Crossref] CR - 3. Kim KS, Choi JH, Kim HM, Kim KP, Kwon YJ, Hwang JH, et al. Hydrocele of the canal of Nuck in a female adult. Arch Plast Surg. 2016;43(5):476–8. [Crossref] CR - 4. Nava CM, Geng B, Litchinko A, Jaccard C, Egger B. Cyst of the canal of Nuck in an adult female patient: a case report on surgical management. Int J Surg Case Rep. 2025;126:110807. [Crossref] CR - 5. Singh A, Chauhan E, Kalantri A, Gupta S. Hydrocele and endometriosis of the canal of Nuck in two adults: a look at the imaging features. BMJ Case Rep. 2023;16(10):e255970. [Crossref] CR - 6. European Journal of Case Reports in Internal Medicine. Going against the grain: a case report of an endometriosis in the canal of Nuck [Internet]. Available from: https://www.ejcrim.com/index.php/EJCRIM/article/view/5024. Accessed: 2025 Jul 20. [Crossref] CR - 7. Okoshi K, Mizumoto M, Kinoshita K. Endometriosis-associated hydrocele of the canal of Nuck with immunohistochemical confirmation: a case report. J Med Case Rep. 2017;11(1):354. [Crossref] UR - https://dergipark.org.tr/tr/pub/jocass/issue//1753208 L1 - https://dergipark.org.tr/tr/download/article-file/5100678 ER -