@article{article_1758337, title={Evaluation of Inflammatory Response with Complete Blood Count Parameters in Abdominal, Vaginal, and Laparoscopic Hysterectomy Techniques: A Retrospective Cohort Study}, journal={Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi}, volume={22}, pages={367–372}, year={2025}, DOI={10.38136/jgon.1758337}, author={Halilzade, İnci and Halilzade, Mohammad İbrahim and Taş, Erdem}, keywords={abdominal histerektomi, vajinal histerektomi, laparoskopik histerektomi, WBC, NLR, PLR, DNI}, abstract={Aim: The aim of our study was to evaluate the inflammatory response in abdominal hysterectomy (AH), vaginal hysterectomy (VH), and laparoscopic hysterectomy (LH) techniques using complete blood count (CBC) parameters and to demonstrate the role of the delta neutrophil index (DNI) in hysterectomy types. Materials and Methods: The study included 251 patients. Patients were divided into three groups: AH, VH, and LH. Patient demographic characteristics, operational characteristics, and CBC results (white blood cell (WBC), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and DNI) were compared separately for the three groups before surgery, at 6 hours postoperatively, and at 24 hours postoperatively. Results: The age and menopause rate of patients in the VH (n=84) group were higher than the LH (n=82) and AH (n=84) groups (P < 0.05). The operative time was longest in the LH group and shortest in the AH group (P < 0.05). The highest WBC, NLR, and PLR levels at postoperative 6th hour were in the AH group, and the lowest levels were in the VH group (P < 0.01). There were no significant differences in serum DNI levels between the LH, AH, and VH groups preoperatively and at the 6th and 24th hours postoperatively. Conclusion: We found the highest postoperative inflammatory response in the AH group and the lowest in the VH group, and contrary to many studies, we found that LH patients had an average inflammatory response. Although DNI increased in the postoperative inflammatory process, there was no difference between the AH, LH, and VH groups.}, number={3}, publisher={T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi}