TY  - JOUR
T1  - Epidemiology of viral respiratory tract infections in pediatric ICU: a single-center study in Turkiye
TT  - Pediatrik yoğun bakımda viral solunum yolu enfeksiyonlarının epidemiyolojisi: Türkiye'den tek merkezli bir çalışma
AU  - Gülyüz, Abdulgani
AU  - Poyraz, Nazan
AU  - Yaldız Ataş, Sıla
PY  - 2025
DA  - October
Y2  - 2025
DO  - 10.32322/jhsm.1759588
JF  - Journal of Health Sciences and Medicine
JO  - J Health Sci Med /JHSM /jhsm
PB  - MediHealth Academy Yayıncılık
WT  - DergiPark
SN  - 2636-8579
SP  - 1099
EP  - 1104
VL  - 8
IS  - 6
LA  - en
AB  - Aims: This study aims to evaluate the distribution of viral agents and their relationship with clinical parameters in pediatric patients with respiratory tract infections in the pediatric intensive care unit (PICU) of MALATYA Training and Research Hospital during 2024.Methods: This retrospective observational study included 257 patients admitted to the PICU with a prediagnosis of respiratory tract infection between January 1 and December 31, 2024. Nasopharyngeal swab samples obtained from the patients were analyzed by multiplex PCR method. Demographic data, laboratory data and clinical course of the patients were recorded and statistical analysis was performed.Results: The most common viral agents were rhinovirus/enterovirus (36.6%) and respiratory syncytial virus (RSV) (31.5%). The comorbidity rate was 38.1%. RSV infections were associated with significantly longer ICU stay compared to rhinovirus (mean 6.8 days vs. 4.3 days in the rhinovirus group, p=0.008). According to multiple regression analysis, age, CRP level and presence of comorbidities were determined as factors that significantly affected the length of stay (p
KW  - Pediatric intensive care
KW  - viral agents
KW  - rhinovirus
KW  - respiratory syncytial virus
KW  - comorbidity
KW  - PCR
N2  - Amaç:Bu çalışma, Malatya Eğitim ve Araştırma Hastanesi Çocuk Yoğun Bakım Ünitesi'nde (ÇYBÜ) 2024 yılı boyunca solunum yolu enfeksiyonu tanısıyla izlenen çocuk hastalarda viral etkenlerin dağılımını ve bu etkenlerin klinik parametrelerle ilişkisini değerlendirmeyi amaçlamaktadır.Yöntem:Retrospektif olarak planlanan bu gözlemsel çalışmaya 1 Ocak – 31 Aralık 2024 tarihleri arasında solunum yolu enfeksiyonu ön tanısı ile ÇYBÜ’ne yatırılan 257 hasta dahil edilmiştir. Hastalardan elde edilen nazofaringeal sürüntü örnekleri multiplex PCR yöntemi ile analiz edilmiştir. Hastaların demografik bilgileri, laboratuvar verileri ve klinik seyri kayıt altına alınarak istatistiksel analizler yapılmıştır.Bulgular:En sık saptanan viral etkenler rinovirüs/enterovirüs (%36,6) ve RSV (%31,5) olmuştur. Komorbidite oranı %38,1 olarak tespit edilmiştir. RSV enfeksiyonları, rinovirüse kıyasla anlamlı olarak daha uzun yoğun bakım yatışı ile ilişkilendirilmiştir (ortalama 6,8 gün iken rinovirüs grubunda 4,3 gündü, p=0.008). Çoklu regresyon analizine göre yaş, CRP düzeyi ve komorbidite varlığı yatış süresini anlamlı derecede etkileyen faktörler olarak belirlendi (p
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UR  - https://doi.org/10.32322/jhsm.1759588
L1  - https://dergipark.org.tr/tr/download/article-file/5129005
ER  -