@article{article_1761284, title={Brunner Gland Adenoma: A Rare Case Presenting with Upper Gastrointestinal Bleeding}, journal={Cerasus Journal of Medicine}, volume={2}, pages={168–172}, year={2025}, DOI={10.70058/cjm.1761284}, author={Çinar, İlkay and Aydın, Gökhan}, keywords={Brunner bezi adenomu, duodenal polip, gastrointestinal kanama, endoskopik polipektomi, benign duodenal tümör}, abstract={Introduction Brunner gland adenoma is a rare benign tumor originating from the excessive proliferation of Brunner glands in the duodenum. It accounts for approximately 1% of all duodenal tumors and is often asymptomatic. However, in some cases, it may cause gastrointestinal bleeding, obstruction, or dyspeptic symptoms. Case Presentation: We present the case of a 58-year-old female who was admitted to the emergency department with fatigue, nausea, vomiting, and melena. She had a history of coronary artery disease and was on daily acetylsalicylic acid therapy. Upper gastrointestinal endoscopy revealed a pedunculated polyp measuring 1.8 × 1.6 × 1 cm in the duodenal bulb, with an irregular clotted surface causing partial luminal obstruction. Endoscopic polypectomy was successfully performed, and histopathological examination confirmed the diagnosis of Brunner gland adenoma. No malignancy or dysplasia was detected. Discussion: Brunner gland adenomas should be considered in the differential diagnosis of duodenal polyps detected during endoscopic evaluation. Although typically benign, these lesions can lead to significant clinical symptoms and may mimic malignancy. Endoscopic polypectomy is the preferred treatment for small and pedunculated lesions, while surgical excision may be required for larger or broad-based lesions. Careful follow-up is essential to monitor for recurrence or complications.}, number={3}, publisher={Giresun Eğitim ve Araştırma Hastanesi}, organization={yok}