TY  - JOUR
T1  - The effect of liver cirrhosis on early postoperative complications after sleeve gastrectomy: a matched case-control study
TT  - Karaciğer sirozunun sleeve gastrektomi sonrası erken postoperatif komplikasyonlara etkisi: eşleştirilmiş vaka-kontrol çalışması
AU  - Ocaklı, Serhat
AU  - Canlıkarakaya, Fırat
AU  - Altunsaray, Ayten
AU  - Doğan, İbrahim
AU  - Chouseın, Bourak
AU  - Karabacak, Harun
AU  - Ceylan, Cengiz
AU  - Banlı, Oktay
PY  - 2025
DA  - October
Y2  - 2025
JF  - Journal of Medicine and Palliative Care
JO  - J Med Palliat Care / JOMPAC / Jompac
PB  - MediHealth Academy Yayıncılık
WT  - DergiPark
SN  - 2717-7505
SP  - 507
EP  - 510
VL  - 6
IS  - 5
LA  - en
AB  - Aims: Obesity-related liver disease begins with non-alcoholic fatty liver disease (NAFLD) and may progress to non-alcoholic steatohepatitis (NASH) and cirrhosis. Sleeve gastrectomy (SG) is an effective treatment, though some patients only seek it after liver damage has occurred. While cirrhosis increases surgical risk, SG may still be viable for selected child A patients, with potential benefits outweighing the risks, as noted in recent guidelines. This study aims to evaluate the impact of liver cirrhosis on first 30-day postoperative complications following SG. Methods: A 1:3 retrospective matched case-control design was used. Early postoperative complications were assessed using the Clavien-Dindo classification. Seven patients with cirrhosis (cases) and 21 without (controls) were included. Results: The median age was 51 (44-62) in the case group and 51 (44-61) in controls. Median body-mass index (BMI) was 45.7 kg/m2 (39.9-48.4) for cases and 44.7 kg/m2 (40.3-47) for controls, with no significant demographic differences. Excluding the 3-points for cirrhosis, the median Charlson Comorbidity Index (CCI) for other comorbidities was 2 in both groups. In the cirrhotic group, 3 had CDC grade 1 and 1 had grade 2 complications; in the control group, 2 had grade 1 and 1 had grade 2. No severe complications (Clavien-Dindo >IIIa) occurred, and there was no significant difference in minor complications (p
KW  - Cirrhosis
KW  - sleeve gastrectomy
KW  - obesity
KW  - complication
KW  - bariatric surgery
N2  - Amaç: Obeziteyle ilişkili karaciğer hastalığı, yağlı karaciğer hastalığı (NAFLD) ile başlar ve non-alkolik steatohepatit (NASH) ve siroza ilerleyebilir. Bariatrik cerrahi (BS) etkili bir tedavi yöntemi olmasına rağmen, bazı hastalar bu cerrahiyi ancak karaciğer hasarı geliştikten sonra talep etmektedir. Siroz cerrahi riskini artırsa da, yakın zamanda yayımlanan kılavuzlarda belirtildiği üzere, seçilmiş Child A sınıfı hastalarda potansiyel faydalar risklerden daha ağır basabileceğinden bariatrik cerrahi hala uygulanabilir bir seçenek olabilir. Bu çalışmanın amacı, karaciğer sirozunun bariatrik cerrahi sonrası ilk 30 gün içindeki erken postoperatif komplikasyonlar üzerindeki etkisini değerlendirmektir.Yöntemler: Çalışma, 1:3 oranında eşleştirilmiş, retrospektif bir vaka-kontrol tasarımı kullanılarak gerçekleştirilmiştir. Erken postoperatif komplikasyonlar Clavien-Dindo sınıflaması kullanılarak değerlendirilmiştir. Çalışmaya sirozu olan yedi hasta (vakalar) ve sirozu olmayan 21 hasta (kontroller) dahil edilmiştir.Bulgular: Vaka grubundaki ortalama yaş 52, kontrol grubundakilerde ise 51.1 idi. Ortalama vücut kitle indeksi (VKİ) vakalarda 46.7 kg/m², kontrollerde ise 46.2 kg/m² olup, demografik özellikler açısından anlamlı bir fark bulunmamıştır. Siroz dışı ek hastalıkları değerlendiren Charlson Komorbidite İndeksi (CCI) her iki grupta da 2 idi. Siroz grubunda 3 hastada Grade 1, 1 hastada ise Grade 2 komplikasyon görülürken, kontrol grubunda 2 hastada Grade 1 ve 1 hastada Grade 2 komplikasyon saptanmıştır. Ciddi komplikasyonlar (Clavien-Dindo >IIIa) gözlenmemiş olup, minör komplikasyonlar açısından anlamlı bir fark bulunmamıştır (p
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UR  - https://dergipark.org.tr/tr/pub/jompac/issue//1767228
L1  - https://dergipark.org.tr/tr/download/article-file/5163333
ER  -