@article{article_190196, title={The effect of induced hypotension and tissue trauma on renal function in patients undergoing spinal surgery}, journal={Acta Orthopaedica et Traumatologica Turcica}, volume={32}, pages={5–7}, year={2006}, DOI={10.3944/aott.v32i1.2218}, author={Benli, Teoman and Duman, Evrim and Goksan, Gulnur and Yazicioglu, Dilek}, abstract={Induced hypotensive anesthesia is the most widely used method to avoid blood loss that may even be life-threatening during spinal surgery. Surgery causes considerable trauma to bone and muscle that, along with hypotensive anesthesia, might be anticipated to impair renal function. In this study, the effect of induced hypotension on renal function in 140 patients who had spinal surgery was examined. Blood and urine tests for electrolytes, creatinine, BUN, and creatine kinase were performed both preoperatively and postoperatively, and the results were compared. An average of 280 cc of blood was replaced to compensate for an average blood loss of 300 cc. All biochemical tests gave results within normal limits. However, there was a mild hypokalemia and a mild hyponatremia in the early postoperative period which corrected in a short time. A mild decrease in ceratinine clearance (114 ml/min/1.73m2) increased to an average of 130 ml/min/1.73m2 soon after the operation. These findings show that induced hypotensive anesthesia does not impair renal function while providing the surgeon with a bloodless operative field during spinal surgery.}, number={1}, publisher={Turkish Association of Orthopaedics and Traumatology}