TY  - JOUR
T1  - Squamous cell carcinoma arising from chronic osteomyelitis
AU  - Alami, Mohammed
AU  - Mahfoud, Mustapha
AU  - Bardouni, Ahmed
AU  - Berrada, Mohamed
AU  - Yaacoubi, Moradh
PY  - 2011
DA  - July
JF  - Acta Orthopaedica et Traumatologica Turcica
PB  - Turkish Association of Orthopaedics and Traumatology
WT  - DergiPark
SN  - 1017-995X
SP  - 144
EP  - 148
VL  - 45
IS  - 3
LA  - en
AB  - Objectives: Our aim was to present the results from a retrospective study of 7 cases of squamous cell carcinoma arising from chronic osteomyelitis.Methods: We treated seven cases of chronic osteomyelitis related squamous cell carcinoma between 1993 and 2005. The patients had an average age of 54.5 (range: 38-71) years, with a male predominance (6 men, 1 woman). We analyzed the time up to cancerization, the localization and histopathological type of the carcinoma, and the type and result of the treatment.Results: The mean time between the occurrence of the skin lesions and the diagnosis of malignant degeneration was 24.5 (range: 9 to 40) years. The carcinoma resulted from tibia osteomyelitis in 4 cases, femur osteomyelitis in 2 cases and humerus osteomyelitis in one. The pathological examination showed five cases of a well differentiated squamous cell carcinoma with bone invasion, and two cases of invasive squamous cell carcinoma. The treatment consisted of amputation in all but one patient, who refused the amputation. The six amputee patients did not show local recurrence or metastatic dissemination over a period of five years.Conclusion: Amputation appears to be an effective treatment method in squamous carcinoma secondary to chronic osteomyelitis.
KW  - Chronic osteomyelitis
KW  - malignant tumors
KW  - squamous cell carcinoma
UR  - https://dergipark.org.tr/tr/pub/aott/issue//191975
L1  - https://dergipark.org.tr/tr/download/article-file/169977
L1  - https://dergipark.org.tr/tr/download/article-file/169978
ER  -