@article{article_202390, title={Six Cases of Megalencephalic Leukoencephalopathy with Subcortical Cysts in a family}, journal={Journal of Pediatric Sciences}, volume={6}, year={2014}, DOI={10.17334/jps.02063}, author={Narayan, Shamrendra and Agarwal, Dipti and Verma, Vandna and Prajapati, Nirmal}, keywords={megalencephalic leukoencephalopathy, subcortical cysts}, abstract={<table width="100%" border="0" cellspacing="0" cellpadding="0"> <tbody> <tr> <td width="620"> <p> <strong> <span style="font-size: medium;">Abstract </span> </strong> </p> <p> <span style="font-size: medium;"> We present a case series of 6 children of Megalencephalic leukoencephalopathy with subcortical cysts. It is a very rare leukodystrophy that is characterized by macrocephaly , a slowly progressive clinical course and fatal outcome. Clinical presentation and MRI scans are the mainstay of diagnosis. 6 of 7 children from the same parents were affected suggesting variation from autosomal recessive pattern.   </span> </p> </td> </tr> <tr> <td width="620"> <p>  </p> <p> <span style="font-size: medium;">  </span> </p> <p> <span style="font-size: medium;">  </span> </p> </td> </tr> </tbody> </table>}, publisher={Bilal YILDIZ} }