TY - JOUR T1 - Liken sklerozus zemininden gelişen vulva karsinomu: Olgu sunumu TT - Vulvar carcinoma which arised within background of lichen sclerosus: Case report AU - Kiremitçi, Ümmühan AU - Karagülle, Şerife Günel AU - Erdemir, Aslı Turgut AU - Topçu, Elif AU - Bozkurt, Serpil AU - Geçer, Melin Özgün AU - Bozkurt, Erol PY - 2005 DA - April DO - 10.16948/zktb.31222 JF - Zeynep Kamil Tıp Bülteni PB - Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH WT - DergiPark SN - 1300-7971 SP - 119 EP - 121 VL - 36 IS - 3 LA - tr AB - Vulva karsinomu nadir olup çoğunlukla 60 yaşın üstündeki kadınlarda görülür. Nedeni halen çok açık olmamakla birlikte etyopatogenezde başlıca Human Papilloma Virüsü (HPV) ve liken sklerozus suçlanmaktadır. Biz vulvasında, liken sklerozus zemininden gelişmiş, iyi diferensiye, invaziv skuamöz hücreli kanseri olan 36 yaşında bir kadın olgu sunmaktayız. KW - Vulva neoplazmları KW - Neoplazmlar KW - yassı hücreli KW - Vulvar liken sklerozus N2 - Vulvar carcinoma is a rare disorder that frequently occurs in women at 60 year or older. No specific factors have been clearly identified as causative but HPV and lichen sclerosus are thought to be the predisposing factors. We are presenting a 36 year old women who has well differentiated, invasive squamous cell carcinoma at her vulva and we think the cancer has developed within a background of lichen sclerosus. CR - Mehta RK, Rytına E, Sterling JC. Treatment of verrucous carcinoma of vulva with asitretin Br J Dennatol 2000; 142:1195-1198. CR - Creasman WT. Malignant Vulvar Lesions: e- Medicine Journal 2002 CR - Ive FA .The Umbilical, Perianal and Genital Regions.In: Champion RH, Burton JL, Ebling FJG eds. Rook /Wilkinson /Ebling Textbook of Dermatology. 5. baskı. Oxford: Blackwell sci.pub, 1992;2851-7 CR - Scurry J. Does lichen sclerosus play a central role in the pathogenesis of human papillomavirus negative vulvar squamous cell carcinoma? The itch- scratch- lichen sclerosus hypothesis. Int J Gynecol Cancer 1999; 9: 89-97 CR - Carli P, De MagnisA, Mannone F, Botti E, Taddei G, Cattaneo A. Vulvar carcinoma associated with lichen sclerosus. Experience at the Florence, Italy, Vulvar Clinic.J Reprod Med 2003; 48: 313-8 CR - Rowell NR, Goodfield MJD. The 'Connective Tissue Diseases'. In : Champion RH, Burton JL, Ebling FJG eds. Rook /Wilkinson /Ebling Textbook of Dermatology. 5.baski. Oxford: Blackwell sci.pub, 1992; 2269-2273 CR - Edwards L. Diseases and Disorders of the Anogenitaia of Females. In: Freedberg İM et al eds CR - Fitzpatrick's Dermatology in General Medicine CR - 5.baskı. New York: Me Graw-Hill, 1999: 1391 CR - Smith YR, Haefner HK. Vulvar lichen sclerosus: pathophysiology and treatment. Am J Clin Dermatol 2004;5(2):105-25 CR - Braun- Falco O, Plewig G, Wolff HH, Burgdorf WHC .Dermatology. 2. tamamen yenilenmiş baskı CR - Berlin: Springer, Verlag, 2000:1472 CR - Carlson JA, Lamb P, Malfetano J, Ambros RA, Mihm MC Jr .Clinicopathologic comparision of vulvar and extragenital lichen sclerosus: histologic variants ,evolving lesions and etiology of 141 cases.Mod Pathol 1998 ; 11(9) 844-54. UR - https://doi.org/10.16948/zktb.31222 L1 - https://dergipark.org.tr/tr/download/article-file/205363 ER -