@article{article_237913, title={SYNTHESIS and ANTIMICROBIAL ACTIVITY of SOME NOVEL QUINOXALINE HYDRAZONES}, journal={Anadolu University Journal of Science and Technology C - Life Sciences and Biotechnology}, volume={4}, pages={31–39}, year={2016}, DOI={10.18036/btdc.57492}, author={Başyiğit, Esra and Acar Çevik, Ulviye and Özkay, Yusuf and Karaca Gençer, Hülya and Uçucu, Ümit}, keywords={Kinoksalin, Hidrazon, Antimikrobiyal aktivite, Mikro-broth dilüsyon}, abstract={<p>A new class of 10 novel quinoxaline hydrazones was synthesized to examine their antimicrobial activity. The structural of the compounds was confirmed by IR, <sup>1 </sup>H-NMR, and MS spectral data and elemental analyses. Antimicrobial activity of the compounds was evaluated against 3 fungal and 7 bacterial strains by Micro-broth dilution assay. All of the synthesized compounds indicated showed significant antibacterial activity against <em>Pseudomonas aeruginosa </em>. Furthermore, antibacterial activity of the 2,4-difluoro substituted compound <strong>4b </strong> displayed two fold better activity than chloramphenicol against this bacterial strain.   </p>}, number={1}, publisher={Eskişehir Teknik Üniversitesi}