TY - JOUR TT - Uzun süreli azathiopürin tedavisi sonrası görülen erüptif melanositik nevüs olgusu AU - Eriş Eken, Zehide AU - Taşkın, Banu AU - Yazıcı, İlker AU - Namdar Çelikkan, Başak AU - Çay, Ömer AU - Çoban, İpek AU - Kuşku Çabuk, Fatmagül AU - Alper, Sibel PY - 2016 DA - September DO - 10.5606/fng.btd.2016.039 JF - İstanbul Bilim Üniversitesi Florence Nightingale Tıp Dergisi PB - Demiroğlu Bilim Üniversitesi WT - DergiPark SN - 2149-4401 SP - 208 EP - 210 VL - 2 IS - 3 KW - Dermoskopi KW - erüptif melanositik nevüs KW - immunsüpresif tedavi KW - melanom N2 - Bu yazıda, otoimmün hepatit tanısı ile çocukluk döneminde aralıklı olarak immünsüpresif tedavi görmüş erüptif melanositik nevüsleri olan 27 yaşında, bir kadın hasta sunuldu. CR - Belloni Fortina A, Piaserico S, Zattra E, Alaibac M. Dermoscopic features of eruptive melanocytic naevi in an adult patient receiving immunosuppressive therapy for Crohn’s disease. Melanoma Res 2005;15:223-4. CR - Smalley KS. Understanding melanoma signaling networks as the basis for molecular targeted therapy. J Invest Dermatol 2010;130:28-37. CR - Gray-Schopfer V, Wellbrock C, Marais R. Melanoma biology and new targeted therapy. Nature 2007;445:851-7. CR - Pollock PM, Harper UL, Hansen KS, Yudt LM, Stark M, Robbins CM, et al. High frequency of BRAF mutations in nevi. Nat Genet 2003;33:19-20. CR - Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM, et al. BRAFE600- associated senescence-like cell cycle arrest of human naevi. Nature 2005;436:720-4. CR - Gray-Schopfer VC, Cheong SC, Chong H, Chow J, Moss T, Abdel-Malek ZA, et al. Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br J Cancer 2006;95:496-505. CR - Maldonado JL, Timmerman L, Fridlyand J, Bastian BC. Mechanisms of cell-cycle arrest in Spitz nevi with constitutive activation of the MAP-kinase pathway. Am J Pathol 2004;164:1783-7. CR - Sekulic A, Colgan MB, Davis MD, DiCaudo DJ, Pittelkow MR. Activating BRAF mutations in eruptive melanocytic naevi. Br J Dermatol 2010;163:1095-8. CR - John JK, Smalley KS. Identification of BRAF mutations in eruptive melanocytic nevi: new insights into melanomagenesis? Expert Rev Anticancer Ther 2011;11:711-4. UR - https://doi.org/10.5606/fng.btd.2016.039 L1 - https://dergipark.org.tr/tr/download/article-file/228311 ER -