@article{article_270371, title={İs Combined Acellular Collagen Matrix and High Tibial Osteotomy Treatment Effective In Osteochondral Defects? Preliminary Study}, journal={Acta Medica Alanya}, volume={1}, pages={2–6}, year={2017}, DOI={10.30565/medalanya.270371}, author={Konya, Mehmet Nuri and Horata, Erdal and Maralcan, Gökhan and Erten, Abdullah Recep and Turamanlar, Ozan}, keywords={Kıkırdak,Yüksek Tibial Osteotomi,Asellüler Kollajen Matris}, abstract={<p class="MsoNoSpacing" style="text-align:justify;"> <b> <span lang="en-us" style="font-size:10pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us"> <br /> </span> </b> </p> <p class="MsoNoSpacing" style="text-align:justify;"> <b> <span lang="en-us" style="font-size:10pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us">Aim: </span> </b> <span lang="en-us" style="font-size:10pt;font-family:Arial, ’sans-serif’;" xml:lang="en-us"> </span> <span style="font-size:10pt;font-family:Arial, ’sans-serif’;"> In this study, we want to compare clinical and radiological results of 12 patient treated with acellular collagen matrix (ACM) and High Tibial osteotomy-cellular collagen matrix(ACM-HTO) combination. </span> </p> <p class="MsoNoSpacing" style="text-align:justify;"> <b style="font-size:.9em;"> <span style="font-size:10pt;font-family:Arial, ’sans-serif’;">Method: </span> </b> <span style="font-size:10pt;font-family:Arial, sans-serif;"> In this study, we evaluated 12 patients with chondral lesion prospectively the years of between 2014- 2016 after ethical approval. Cartilage damage was diagnosed with MRI and cartilage degeneration volume was calculated with Mimics medical image processing software and axis deviation was diagnosed with ortho X-ray. Patients were divided into two groups. ACM only (Group 1) and ACM- HTO (Group 2). </span> </p> <p class="MsoNoSpacing" style="text-align:justify;"> <b> <span style="font-size:10pt;font-family:Arial, ’sans-serif’;"> </span> </b> </p> <p> <b>  </b> </p> <b> </b> <b style="font-size:.9em;"> <span style="font-size:10pt;font-family:Arial, ’sans-serif’;">Results: </span> </b> <span style="font-size:10pt;font-family:Arial, sans-serif;"> ACM only group consists of 5 patients. Preoperative mean of chondral lesion volume was 77.11±137.5 (0.27-321.61). Post-operative mean Knee  score was 175.20±24.4(150-203) and chondral lesion volume was 0.3±0.03(0-0.8). ACM-HTO group consists of 7 patients. Preoperative mean of chondral lesion volume was 112.72±239(0.27- 653). Post-operative mean of HSS score was 155±20.4(135-183) and chondral lesion volume was 0.26±0.09(0-0.69). </span> <p class="MsoNoSpacing" style="text-align:justify;"> <b style="font-size:.9em;"> <span style="font-size:10pt;font-family:Arial, ’sans-serif’;"> <br /> </span> </b> </p> <p class="MsoNoSpacing" style="text-align:justify;"> <b style="font-size:.9em;"> <span style="font-size:10pt;font-family:Arial, ’sans-serif’;">Conclusion: </span> </b> <span style="font-size:10pt;font-family:Arial, sans-serif;"> According to these results, all patients’ HSS scores and Cartilage volume are increased, but there were no significant differences were found between two groups. </span> </p>}, number={1}, publisher={Alanya Alaaddin Keykubat Üniversitesi}