TY  - JOUR
TT  - The role of anti-mullerian hormone for determining the ovarian reserve of IVF patients
AU  - Yeniçeri, Haççe
AU  - Ürünsak, İbrahim F.
AU  - Sucu, Mete
AU  - Çetin, Cihan
AU  - Özsürmeli, Mehmet
AU  - Khatib, Ghanim
PY  - 2017
DA  - March
Y2  - 2016
DO  - 10.17826/cutf.270412
JF  - Cukurova Medical Journal
JO  - Cukurova Med J
PB  - Çukurova Üniversitesi
WT  - DergiPark
SN  - 2602-3032
SP  - 19
EP  - 26
VL  - 42
IS  - 1
KW  - Gebelik
KW  - in vitro fertilizasyon
KW  - ovaryum fonksiyon testleri
N2  - Purpose: The puspose of this study was to find thelevel of effectiveness and reliability of AMH (anti-müllerian hormone) inindicating the over reserve of IVF patients in comparison with other reserveindicators used.Materials and Methods: The study included 89 infertile couples ages between 18 and 45.Basal serum FSH, LH, E2, prolactin, fT3, fT4 and TSH, AMH levels of femalepatients were measured in the 3rd day of menstruation. Ovary volume andAFC(antral follicle count) were determined through transvaginal ultrasound. Inour study, all patients were subjected to long protocol with GnRH agonist.Oocyte numbers equal to or higher than 4 were included in the “good response”group and oocyte numbers lower than 4 were included in the “poor response”group. Afterwards, the results obtained were statistically compared with otherparameters used for determination of ovarian reserve.Results. Significant differences were present between two groups in terms of age, serum FSH,AMH levels, hCG day E2 levels, number of antral follicles, hCG day folliclenumbers and mature oocyte numbers. When the cutoff value for AMH was taken tobe 0,24 ng/ml, sensitivity and specifity were determined to be 82.1% and 72.7%respectively. Conclusion: There is a strong relationship between serum AMH level and the ovarianresponse of the patients. Besides, AMH levels were determined to be in relationwith the pregnancy rate.
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UR  - https://doi.org/10.17826/cutf.270412
L1  - https://dergipark.org.tr/tr/download/article-file/264857
ER  -