TY  - JOUR
TT  - Effect of tumor size on survival in pN0M0 non-small cell lung cancer patients
AU  - Kocaman, Gökhan
AU  - Yüksel, Cabir
AU  - Yenigün, Bülent Mustafa
AU  - Sakallı, Mehmet Ali
AU  - Karasoy, Durdu
AU  - Özkan, Murat
AU  - Enön, Serkan
AU  - Kayı Cangır, Ayten
PY  - 2016
DA  - December
JF  - CURRENT THORACIC SURGERY
JO  - CTS
PB  - Turkish Society of Thoracic Surgery (TSTS)
WT  - DergiPark
SN  - 2548-0316
SP  - 12
EP  - 15
VL  - 1
IS  - 1
KW  - Non-small cell lung cancer
KW  - tumor size
KW  - survival
N2  - Background: Tumor size is one of the major prognostic determinants of non-small cell lung cancer (NSCLC). In the present study, we evaluated the effect of tumor size on survival in pN0M0 NSCLC patients. Materials and Methods: Between 1994 and 2013, 1975 NSCLC patients underwent surgery in our center. The study included 774 NSCLC patients with pathological stage N0M0, and these patients were divided into 8 groups according to tumor diameter, as follows, Group 1: 0-10 mm, Group 2: 11-20 mm, Group 3: 21-30 mm, Group 4: 31-40 mm, Group 5: 41-50 mm, Group 6: 51-60 mm, Group 7: 61-70 mm, and Group 8: > 70 mm. We aimed to evaluate the prognostic effect of tumor size on overall survival and to determine a cut-off point for tumor size. Results: The 5 year overall survival rate for groups 1 to 8 were 85.6%, 81.3%, 68.6%, 62.2%, 55%, 54.2%, 54.3%, and 45.6%, respectively. The mean follow-up time was 43.8 months. In multivariate analysis, age, tumor size, and surgical resection type had an independent prognostic value on survival. Conclusions: Tumor size is an independent prognostic factor for pN0M0 NSCLC patients. A tumor size of 4 cm was found to be the most suitable cut-off point for survival which may be of help in decision-making for adjuvant chemotherapy.
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UR  - https://dergipark.org.tr/tr/pub/currthoracsurg/issue//282147
L1  - https://dergipark.org.tr/tr/download/article-file/263968
ER  -