TY - JOUR TT - TÜRKİYE’DE BULUNAN VİTİLOGOLU HASTALARIN İŞİTMELERİNİN DEĞERLENDİRİLMESİ An Evaluation of the Hearing Examinations of Vitiligo Patients in Turkey AU - Bakar Dertlioğlu, Selma AU - İynen, İsmail AU - Sapmaz, Emrah AU - Çiçek Posta, Demet PY - 2016 DA - December JF - Bozok Tıp Dergisi PB - Yozgat Bozok Üniversitesi WT - DergiPark SN - 2146-4006 SP - 10 EP - 15 VL - 6 IS - 2 KW - Vitiligo; Odyometri; Transient uyarılmış otoakustik emisyon; Koklear disfonksiyon. N2 - Amaç: Vitiligo, depigmente makula ve belirgin melanosit yıkımıyla karekterize edinsel, idiopatik, otoimmünbir hastalıktır. Çalışma vitilogo hastalarında olası odyolojik anormallikleri saptamak için planlandı. Konvansiyonelodyolojik testlerle (saf ses eşiği ) ve transient otoakustik emisyon (TEOAE) ile vitiligo hastalarında koklearfonksiyonları ölçtük ve kontrol grubuyla karşılaştırdık.Materyal ve Metot: Vitiligolu 32 hasta cinsiyetçe benzer 32 sağlıklı kişi çalışmaya alındı. Odyometrik veTEOAE testleri hasta ve kontrol grubunda yapıldı. Odyometrik ölçümler ses geçirmeyen kabinde saf ses odyometriyleyapıldı. Saf ses eşikleri 250-6000 Hz’de her kulak için ölçüldü.Bulgular: Odyometrik bulgular vitiligolu hastalar ve kontrol grubu arasında 250-6000 Hz arası saf ses eşiklerindefark olmadığını ortaya koydu. Vitiligolu hastalarda saf ses odyogramda sensörinöral işitme kaybı yoktu.Vitiligolu hastalarda saf ses odyometride değişiklik olmasa da transient otoakustik emisyon değerlerindeki düşmelerindış tüy hücrelerini etkilediği düşünülebilir.Sonuç: Konvansiyonel odyometri ile birlikte TEOAE testleri koklear disfonsiyonun erken tanısında güvenilirtestlerdir. Vitiligolu hastalarda hastalığın ilerlemesi ve erken fark edilmesi açısından odyolojik incelemenin rutinolarak yapılması gerektiğini düşünüyoruz.ABSTRACTObjective: Vitiligo is an acquired, idiopathic autoimmune disease characterized by depigmented maculae andmarked with melanocyte destruction. The study was performed to detect possible audiological abnormalitiesin vitiligo patients. We aimed to use conventional audiological tests (pure tone threshold) and altered cochlearfunction, by measuring and analyzing transient evoked otoacoustic emission (TEOAE) testing any subclinicalauditory abnormalities of in patients with vitiligo, compared with controls.Materials and Methods: Thirty-three patients with vitiligo and 32 age- and sex-matched healthy controlcases were included in this study. Audiometric and TEOAE testings for both ears were performed for bothpatients and controls. Audiometric examinations were performed using a pure tone audiometer in a silentcabin. Pure tone thresholds were determined for each ear at frequencies of 250 – 6000 Hz for air conduction.Results: Findings of the audiometric tests indicate that there was no difference between vitiligo and controlgroup cases in pure tone threshold values between 250 and 6000 Hz. There was not sensorineural hearingloss on pure-tone audiogram in patients with vitiligo. Although there is no change in pure tone audiometryin vitiligo patients, it is considered that reductions in transient evoked otoacoustic emission values began toaffect the outer hairy cells.Conclusion: Conventional audiometry with TEOAE testing are reliable tests for the early detection of cochleardysfunction. All patients with vitiligo required routine monitoring and audiological assessments for earlyidentification and monitoring of changes as the disease progresses. CR - 1. Aydogan K, Turan OF, Onart S, Karadogan SK, Tunali S. Audiological abnormalities inpatients with vitiligo. Clin Exp Dermatol. 2006;31(1):110-13. CR - 2. Hong CK, Lee MH, Jeong KH, Cha CI, Yeo SG. Clinical analysis of hearing levels in vitiligo patients. Eur J Dermatol 2009;19(1):50-6. CR - 3. Ardiç FN, Aktan S, Kara CO, Sanli B.High-frequency hearing and reflex latency in patients with pigment disorder. 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A study on otoacoustic emissions and supression effects in patients with vitiligo. Braz J Otorhinolaryngol. 2009;75(1):111-15. CR - 10. Steel KP, Barkway C. Another role for melanocytes: their importance for normal stria vascularis development in the mammalian inner ear. Development. 1989;107(3):453-63. UR - https://dergipark.org.tr/tr/pub/bozoktip/issue//284326 L1 - https://dergipark.org.tr/tr/download/article-file/266435 ER -