TY  - JOUR
TT  - Detection of the involvement of salivary glands in autoimmune diseases of  thyroid gland by using  tc-99m MIBI
AU  - Söylemez, Deniz
AU  - Gümüşer, Gül
AU  - Dursun Rükşen, Ebru
AU  - Sayıt Bilgin, Elvan
PY  - 2017
DA  - March
Y2  - 2016
DO  - 10.16899/gopctd.286073
JF  - Çağdaş Tıp Dergisi
JO  - J Contemp Med
PB  - Rabia YILMAZ
WT  - DergiPark
SN  - 2146-6009
SP  - 67
EP  - 73
VL  - 7
IS  - 1
KW  - Otoimmün tiroid bezi hastalıkları
KW  - tükürük bezleri
KW  - Tc-99m MIBI
N2  - Aim: The aim of this study was to determine the involvement in the salivary glands of the patients with Graves’ Disease, Hashimoto Thyroiditis and controls by detecting the changes of Tc-99m Methoxyisobutylisonitrile (Tc-99m MIBI) uptake.Material and Methods: The study was conducted between January 2008 and December 2009. 19 patients with Graves’ disease (6 men, 13 women), 28 Hashimoto Thyroiditis patients (5 men, 23 women) and 11 euthyroid controls (4 men, 7 women) were evaluated retrospectively. Uptake values of parotid and submandibular glands were calculated by drawing elliptical ROIs (region of interest) and using the formula for uptake calculation.Result: In all three groups, in parotis glands, a statistical significant difference between Tc-99m MIBI uptake was not detected. The Tc-99m MIBI upateke values in submandibular glands were statistically different among patients with Graves’Disease, Hashimoto Thyroiditis, as well as in Control group (p<0.05).Conclusion: We concluded that the different uptake values of Tc-99m-MIBI in submandibular glands in Graves disease and Hashimoto thyroiditis as compared to the control group patient would be results of the histopathological features, such as autoimmunity, high mitochondria number and inflammatory reaction
CR  - Collins J, Gough S. Autoimmunity in thyroid disease. Eur J Nucl Mol Imaging 2002;29(2):s417-24.
UR  - https://doi.org/10.16899/gopctd.286073
L1  - https://dergipark.org.tr/tr/download/article-file/268704
ER  -