TY - JOUR TT - DETERMINATION OF THE EFFECTS OF BISPHENOL A (BPA) ON TOTAL HEMOCYTE COUNTS IN FRESHWATER MUSSELS (Unio mancus) AU - Yıldırım, Feriha AU - Mehrnıa, Leila AU - Aslan, Pınar AU - Yılmaz, Kevser AU - Karasu Benlı, A.Çağlan AU - Erkoç, Figen PY - 2017 DA - February JF - The Turkish Journal Of Occupational / Environmental Medicine and Safety JO - turjoem PB - Engin TUTKUN WT - DergiPark SN - 2149-4711 SP - 157 EP - 157 VL - Volume 2 IS - İssue 1 (1) KW - DETERMINATION OF THE EFFECTS OF BISPHENOL A (BPA) ON TOTAL HEMOCYTE COUNTS IN FRESHWATER MUSSELS (Unio mancus) N2 - Bisphenol A(BPA), is a synthetical chemical that is widely used in polycarbonateplasticsandchemical adhesive resins. There are many studies about that thedevelopment and reproduction system negatively affects in various vertebrateand invertebrate organisms by this chemical which has effects of endocrinedisruptors identified. However, in the determination of the amount of damagethat is still uncertainty and continues research. In this study, total numberof hemocytes were examined to determine the potential damage of BPA on thereproduction and body systems of Unio mancus eucirrus Bourguignat, 1860 (Bivalvia)which is a species of freshwater mussels.The mussels,that have been collected from Sinop-Karasu stream (average lenght 55,2±3,46 mmand average weight 21,97±4,30 g), are carried out in 15 liter tanks by putting15 mussels in each, after 15 days adaptation in dechlorinated tap watersupplied in the laboratory. They were exposed to four different sublethal BPAdoses (0.1 mg/L¸ 1 mg/L¸ 5 mg/L ve 10 mg/L) and at the end of 144 hourshemolymph samples are taken and total hemocytes are counted with a light microscopethrough the hemocytometer. Statistical analysis performed by Kruskal-Wallistest was used.It has beenobserved a significantincrease on the total number of hemocytes of U. mancuswhich are exposed to BPA in comparison to the control group (p <0.05).Accordingly, the determination of the total hemocyte counts infreshwatermusselswas found to be a good biomarkerto examine the effects of BPA that isendocrine disruptor, in freshwater ecosystems. CR - Feriha YILDIRIM, Leila MEHRNIA, Pınar ASLAN, Kevser YILMAZ, A.Çağlan KARASU BENLI, Figen ERKOÇ CR - Gazi Üniversitesi, Teknikokullar, Ankara, 06500 Ankara Üniversitesi, Ankara, 06500 UR - https://dergipark.org.tr/tr/pub/turjoem/issue//306115 L1 - https://dergipark.org.tr/tr/download/article-file/293867 ER -