TY  - JOUR
TT  - ASSESSMENT OF HEAVY METAL LEVELS IN FOLLICULAR FLUID OF WOMEN WITH UNEXPLAINED INFERTILITY
AU  - Çırak, Eyüp
AU  - Erdem, Onur
AU  - Çetınkaya, Serdar
AU  - Ceyhan, Seyit Temel
AU  - Akay, Cemal
AU  - Korkmaz, Cem
AU  - Ulubay, Mustafa
PY  - 2017
DA  - February
JF  - The Turkish Journal Of Occupational / Environmental Medicine and Safety
JO  - turjoem
PB  - Engin TUTKUN
WT  - DergiPark
SN  - 2149-4711
SP  - 171
EP  - 171
VL  - Volume 2
IS  - İssue 1 (1)
KW  - ASSESSMENT OF HEAVY METAL LEVELS IN FOLLICULAR FLUID OF WOMEN WITH UNEXPLAINED INFERTILITY
N2  - The reproductivehealth of women is currently a major worldwide public health problem. The WorldHealth Organization reported that more than 10 % of women are severely affectedby infertility. Environmental factors especially exposure to toxic heavy metalsmay be contributed to development of unexplained infertility because toxicheavy metals may change fertility patterns via endocrine disrupting mechanisms.In addition to this, there are very few studies about the trace element andtoxic heavy metal levels in follicular fluid which considering as target matrixfor unexplained infertility. In this study, we aimed to evaluate the heavymetal and trace element levels in follicular fluid undergoing in vitrofertilization (IVF). For this purpose, follicular fluids were obtained from 19women (age 21-38) who was treated in Department of Obstetrics and Gynecology.Metals levels in the samples were measured using atomic absorptionspectrometric analysis (AAS). Arsenic (As) and lead (Pb) were not found infollicular fluids. The mean levels of cadmium (Cd), aluminium (Al), copper(Cu), zinc (Zn), chromium (Cr) and cobalt (Co) were quantified as 0.93 µg/L,30.6 µg/dl, 46.4 µg/dl, 44.6 µg/dl, 4.15 µg/dl and 4.71µg/dl, respectively. Ourresults showed that these trace and toxic heavy metals must be considered inthe etiology of unexplained infertility. Also further research should becarried out to explain the biological effects of heavy metals in unexplainedinfertility.
CR  - Eyüp ÇIRAK, Onur ERDEM, Serdar ÇETINKAYA, Seyit Temel CEYHAN, Cemal AKAY,
Cem KORKMAZ, Mustafa ULUBAY
CR  - Department of Pharmaceutical Toxicology, Gulhane Military Medical Academy, Ankara, Turkey.
Department of Obstetrics and Gynecology, Gulhane Military Medical Academy, Ankara, Turkey.
UR  - https://dergipark.org.tr/tr/pub/turjoem/issue//306138
L1  - https://dergipark.org.tr/tr/download/article-file/293896
ER  -