@article{article_308491, title={INVERTED PAPILLOMA: A COMPREHENSIVE CLINICAL ANALYSIS}, journal={Journal of Istanbul Faculty of Medicine}, volume={79}, pages={157–162}, year={2017}, DOI={10.18017/iuitfd.308491}, author={Öztürk, Erkan and Çomoğlu, Şenol and Enver, Necati and Öztürk, İlker Erdinç and Çelik, Mehmet and Polat, Beldan and Keleş, Nesil and Değer, Kemal}, keywords={intranazal cerrahi,inverted papillom,neoplazm,paranazal sinüs}, abstract={<p class="MsoNormal" style="text-align:justify;"> <b> <span style="font-size:10pt;">Objective </span> </b> <span style="font-size:10pt;">: This study aimed to
present the clinical and pathological features that effect the recurrence and
malignancy by analysis of results of inverted papilloma surgery performed in
our center. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <b> <span style="font-size:10pt;">Materials
and Methods </span> </b> <span style="font-size:10pt;">: The data of 52 patients whom underwent surgery because of inverted
papilloma at Department of Otorhinolaryngology, Istanbul Faculty of Medicine
between 2008 and 2015 was investigated retrospectively. Demographic datas of
patients, prior surgery, origin of tumor, stage, initial symptoms, and surgical
techniques were evaluated. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <b> <span style="font-size:10pt;">Results </span> </b> <span style="font-size:10pt;">: </span> <span style="font-size:10pt;">The mean age of 52 patients whom were treated from
inverted papilloma was 59.3±12.4, and age range was 32-84. 41 of 52 patients
were male and 11 were female. The distribution of the patients according to
Krouse Staging system was determined such as; 1 of patients was T4, 4 were T2,
41 patients were T3 and 6 were T4. <span> </span> </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <span style="font-size:10pt;">In
all, nine patients were found having squamous cell carcinoma or dysplasia. It
is found that the smoking did not have an effect on recurrence (p=0.289) and
prior surgery (p=0.748), prior surgery history was related to multiple location
(p=0.043). </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <span style="font-size:10pt;">The
mean follow-up period was 49,5±26,6 and minimum and maximum follow-up periods
were 2-96 months. The mean age recurrence time was found as 41.3 months. </span> </p> <p> </p> <p class="MsoNormal" style="text-align:justify;"> <b> <span style="font-size:10pt;">Conclusion: </span> </b> <span style="font-size:10pt;">The most important factor to prevent
the recurrence of inverted papilloma is to determine the location and to excise
exactly. The relation of smoking and old surgery story with the reccurence
could not be proved but it is seen that multiple location was related with
repeating surgery. Larger case series and controlled studies are needed to
obtain clearer statistical results. <b> <span> </span> </b> </span> </p> <p> <b> </b> </p> <b> </b> <p> </p> <p class="MsoNormal"> <b> <i> <span style="font-size:10pt;">Key words: </span> </i> </b> <span style="font-size:10pt;"> <span>İntranasal
surgery; inverted papilloma; neoplasm; paranasal sinus.  </span> </span> </p> <p> </p>}, number={4}, publisher={İstanbul Üniversitesi}