TY - JOUR TT - What is the etiology of abdominal pain? A case of macroamylasemia AU - Çetin, Furkan Bertuğ AU - Dolu, Süleyman AU - Şahintürk, Yasin AU - Uyar, Seyit AU - Bostan, Feyzi AU - Çekin, Ayhan Hilmi PY - 2017 DA - April DO - 10.17941/agd.315853 JF - Akademik Gastroenteroloji Dergisi PB - Türk Gastroenteroloji Vakfı WT - DergiPark SN - 1303-6629 SP - 29 EP - 32 VL - 16 IS - 1 KW - Makroamilazemi KW - akut pankreatit KW - makroenzimler N2 - Serum amylase and lipase levels should be tested in patients admitted to the hospital with abdominal pain to rule out acute pancreatitis. Serum amylase levels may also increase in many systemic diseases and both postsurgical and posttraumatic conditions. Elevated serum amylase levels also may be the side effects of certain drugs. Macroamylasemia should be considered in patients with elevated amylase levels but without any intraabdominal pathologies or drug interactions. Macroamylasemia was the first described and most frequently seen of the macroenzyme types. In these patients, abdominal pain might emerge due to another reason and may incorrectly be referred to as pancreatitis. This situation may cause confusion and lead to both incorrect diagnosis and subsequent inappropriate treatment. Early detection of macroamylasemia not only prevents the misdiagnosis of pancreatitis but also avoids unnecessary treatment or invasive procedures. In this case, we report an 81-year-old macroamylasemia patient who presented with complaints of epigastric pain, blorrhea, nausea, and vomiting for two months.  CR - 1. Pekmezsi S. Akut pankreatitte yaklaşım ve tedavi. In: Göksoy E, Şentürk H. Hepato-Bilier Sistem ve Pankreas Hastalıkları. Sempozyum Dizisi. Ocak 2002;s.239-62. 2. Yalnız M, Asoğlu M, Demirel U, et al. A case of hyperamylasemia: Macroamylasemia? Review of the literature. J Clin Exp Invest 2011;2:98-101. 3. Almiş H, Bucak İH, Çelik V, et al. İyi bilinen, ancak ilk düşünülmeyen bir tanı: Makroamilazemi. İzmir Dr. Behçet Uz Çocuk Hast. Dergisi 2015;5:78-9. 4. Türkçapar N, Özden A. Makroenzimler. Güncel Gastroenteroloji Dergisi. 2006;10:269-72. 5. Özaslan E, Sivri B. Makroenzimler ve makroamilazemi. Güncel Gastroenteroloji Dergisi 1998;2:163-9. 6. Tenner S, Baillie J, DeWitt J, Vege SS; American College of Gastroenterology. American College of Gastroenterology guideline: Management of acute pancreatitis. Am J Gastroenterol 2013;108:1400-15. Erratum in; Am J Gastroenterol 2014;109:302. 7. Rabsztyn A, Green PH, Berti I, et al. Macroamylasemia in patients with celiac disease. Am J Gastroenterol 2001;96:1096-100. 8. Nar H, Uyanıkoğlu A, Aydoğan T, Yenice Y. A celiac patient presenting with hyperamylasemia: A case report. Akademik Gastroenteroloji Dergisi. 2013;12:30-1. 9. Durr HK, Bode C, Krupinski R, Bode CH. A comparison between naturally occuring macroamylasemia and macroamylasemia induced by hydroxyethyl-starch. Eur J Clin Invest 1978;8:189-91. 10. Levitt MD. Clinical use of amylase clearence and isoamylase measurements. Mayo Clin Proc 1979;54:428-431. UR - https://doi.org/10.17941/agd.315853 L1 - https://dergipark.org.tr/tr/download/article-file/306483 ER -