TY  - JOUR
TT  - Chronıc Exposure to Pestıcıdes and Parkınson Dısease
AU  - Kartal, Maide Nur
AU  - Pekşen, Yıldız
AU  - Köksal, Elif Nur
PY  - 2017
DA  - February
JF  - The Turkish Journal Of Occupational / Environmental Medicine and Safety
JO  - turjoem
PB  - Engin TUTKUN
WT  - DergiPark
SN  - 2149-4711
SP  - 33
EP  - 33
VL  - Volume 2
IS  - Issue 1(2)
KW  - Chronıc Exposure to Pestıcıdes and Parkınson Dısease
N2  - Aim andmaterial, Methods: While the prevalence of Parkinson’s disease differs between80,6 and 187 out of hundred thousand in the world, this prevalence has beenreported as 111 out of hundred thousand in our country. The purpose of thisreview, which has been conducted by examining national and internationalliterature, is to attract attention to pesticide exposure which one is of thepreventable risk factors of this disease the prevalence of which is thought toincrease in our aging society. Results: Studies conducted in literatureemphasize the association between pesticide exposure and psychiatric and neurologicaldiseases such as depression, Alzheimer’s disease, Parkinson’s disease and ALS.In some studies, the risk of developing Parkinson’s disease has been found highin individuals who carry GSTP-1 genotype of glutathione which ensures themetabolization of pesticides. In a study conducted in England, pesticides thatcontain especially rotenon and paraquat have been found to be associated withParkinson’s disease. Experiments conducted with animals and cell culturestudies have also shown that pesticide exposure causes neurodegenerativechanges that cause the development of Parkinson’s disease. When compared withEuropean Union countries, the amount of pesticide per hectare in our country isfar more behind these countries. However, in Mediterranean, Aegean and Marmararegions where agriculture is carried out intensively, pesticide use hasapproached the level of developed countries. Thus, pesticide residues on foodcome out as a factor that threatens public health. Conclusion: Studiesconducted show that chronic pesticide exposure can cause Parkinson’s diseasewith neurodegenerative processes. In line with the data obtained, it has beenconcluded that primary and secondary protection measures should be conducted tominimize the exposure of both agriculture workers as those who apply pesticideand consumers who will be exposed to pesticide residues.     Keywords:pesticide,Parkinson’s disease, biocidal products
CR  - Maide Nur Kartal, Yıldız Pekşen, Elif Nur Köksal 
Ondokuz Mayıs Unıversty Departments Of Public Health, Samsun
Public Health Administration, Giresun
UR  - https://dergipark.org.tr/tr/pub/turjoem/issue//319673
L1  - https://dergipark.org.tr/tr/download/article-file/311731
ER  -