TY  - JOUR
TT  - A Therapeutic Challenge: Management of Atrial Thrombus
AU  - Burç Deşer, Serkan
AU  - Demirağ, Mustafa Kemal
PY  - 2016
DA  - December
DO  - 10.5799/jcei.328366
JF  - Journal of Clinical and Experimental Investigations
JO  - J Clin Exp Invest
PB  - Aydın ECE
WT  - DergiPark
SN  - 1309-8578
SP  - 278
EP  - 282
VL  - 7
IS  - 4
KW  - Thrombus
KW  - atrium
KW  - treatment
N2  - Introduction: Primary cause of atrial thrombi include atrial fibrillation, foreign bodies inside the atrium such ascatheters and pacemaker leads, emboli of deep venous thrombus and primary or metastatic tumors of the heart. Wereview the clinical features, epidemiology, diagnosis and treatment of nine intriguing cases with atrial thrombus.Methods: This is a retrospective study of nine patients (seven female (78%), two male (33%)) who were diagnosedwith atrial thrombi (average age of 50 ± 12 years) and were treated at the Ondokuz Mayis University, Department ofCardiovascular Surgery from February 2014 to January 2015. Among them, six patients had atrial fibrillation (onemale, five female), seven patients were suffering from dispne and orthopnoea, five patients were suffering from legswelling, seven patients had a history of hypertension and three patients had a history of mitral valve replacementsurgery.Results: All patients underwent surgery except one. Four patients recovered uneventfully and discharged with oralanticoagulation (warfarin) therapy (adjusted to maintain an international normalized ratio of INR between two andthree times). Five of nine patients (55%) died after surgery.Conclusion: The response to the thrombolytic therapy is poor, mostly ineffective and unsafe so it is oftenrecommended as a bridge to surgery. In patients diagnosed with mechanical mitral valve thrombosis, medical therapyhas the possibility of end organ emboli and also fail to resolve the organised thrombus on the stuck valve. On theother hand surgery does not always give satisfactory results. J Clin Exp Invest 2016; 7(4): 278-282
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UR  - https://doi.org/10.5799/jcei.328366
L1  - https://dergipark.org.tr/tr/download/article-file/324764
ER  -