TY  - JOUR
TT  - Benign Endometrial Polyp and Primary Endometrial Small Cell Neuroendocrine Carcinoma Confined to the Polyp: A Rare Association
AU  - Oltulu, Pembe
AU  - Uğurluoğlu, Ceyhan
AU  - Uğur, Ayşenur
AU  - Fındık, Sıdıka
AU  - Tavlı, Lema
PY  - 2016
DA  - March
DO  - 10.5799/jcei.328701
JF  - Journal of Clinical and Experimental Investigations
JO  - J Clin Exp Invest
PB  - Aydın ECE
WT  - DergiPark
SN  - 1309-8578
SP  - 106
EP  - 109
VL  - 7
IS  - 1
KW  - Small cell carcinoma
KW  - endometrial polyp
KW  - neuroendocrine tumor
KW  - endometrium
N2  - Neuroendocrine tumors (NETs) are a heterogeneous group of tumoral lesions originating from diffuse endocrine systemcells. They occur mostly in the gastrointestinal system and the lung. Primary NETs of the female reproductive tract arerare. In a widely used classification, primary small cell neuroendocrine carcinomas (SCNECs) and large cell neuroendocrinecarcinomas (LCNECs) of the endometrium were included in a subgroup of poorly differentiated neuroendocrinecarcinomas. SCNECs of the endometrium are very rare and they are often combined with other epithelial neoplasms.Their myometrial and extrauterine invasions are common during the initial diagnosis due to their aggressive behaviors.In this article, we present a rare case of primary endometrial SCNEC detected within the benign endometrial polyp andwithout invasion of myometrium and extrauterine tissues in a 70-year-old female patient presenting with postmenopausalbleeding. Histopathologically, the tumor cells showed positive staining with Synaptophysin, the Ki-67 labelingindex was 80-90%, the mitotic index was 15/10 per HPF and there was no necrosis and lymphovascular invasion. J ClinExp Invest 2016; 7 (1): 106-109
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UR  - https://doi.org/10.5799/jcei.328701
L1  - https://dergipark.org.tr/tr/download/article-file/325229
ER  -