TY  - JOUR
TT  - An Acute Disseminated Encephalomyelitis Case due to Mycobacterium tuberculosis
AU  - Özden, Hale Turan
PY  - 2016
DA  - March
DO  - 10.5799/jmid.328766
JF  - Journal of Microbiology and Infectious Diseases
JO  - J Microbil Infect Dis
PB  - Aydın ECE
WT  - DergiPark
SN  - 2146-3158
SP  - 28
EP  - 31
VL  - 6
IS  - 1
KW  - Acute disseminated encephalomyelitis
KW  - tuberculosis
N2  - Acute disseminated encephalomyelitis (ADEM) is an inflammatory and demyelinating disorder of the central nervoussystem that is characterized by multifocal involvement of the white matter. Our patient was a 27-year-old female patientwho had given birth to a baby with caesarean in another hospital. After four days upon the parturition, she was admittedto our hospital’s general intensive care unit with a poor general status, confusion and a fever. She was diagnosedwith ADEM according to the clinical, laboratory and radiological findings. In addition to her antibiotic treatment (meropenem)that had been given in the previous health care facility, corticosteroid therapy was also started. The patientpassed away due to the ventilator-associated pneumonia infection on the 10th day of her admission. Mycobacteriumtuberculosis proliferation was observed in the cerebrospinal fluid after her death. As it is reported in literature, tuberculosisis a rare cause of ADEM. In conclusion, it should be noted that M. tuberculosis can be a rare cause of ADEM inregions where the disease is endemic. J Microbiol Infect Dis 2016;6(1): 28-31
CR  - 1. Murthy JM. Acute disseminated encephalomyelitis. Neurol India. 2002;50:238-243.
CR  - 2. Stonehouse B, Gupte G, Wassmer E, Whitehouse WP. Acute disseminated encephalomyelitis: recognition in the hands of general pediatricians. Arch Dis Child. 2003;88:122-124.
CR  - 3. Masoodi I, Farooq O, Ahmad I, et al. Acute disseminated encephalomyelitis as the first presentation of CNS tuberculosis: report of a case with brief review. Ger Med Sci 2010;18;8: Doc32. doi: 10.3205/000121.
CR  - 4. Özhan M, Aydogan ÖT, Kumral E. Acute disseminated encephalomyelitis following pulmonary tuberculosis. Turkish Resp J. 2005;6:161-163.
CR  - 5. van der Knaap MS, Valk J. Acute disseminated encephalomyelitis and acute hemorrhagic encephalomyelitis. In: Magnetic Resonance of Myelination and Myelin Disorders, 3rd edn, Springer, New York. 2005:604.
CR  - 6. Ketelslegers IA, Visser IE, Neuteboom RF, et al. Disease course and outcome of acute disseminated encephalomyelitis is more severe in adults than in children. Mult Scler. 2011;17:441-448.
CR  - 7. Schwarz S, Mohr A, Knauth M, et al. Acute disseminated encephalomyelitis: a follow-up study of 40 adult patients. Neurology. 2001;56:1313-1318.
CR  - 8. Thwaites GE, Tran TH. Tuberculous meningitis: Many questions, too few answers. Lancet Neurol. 2005:4:160-170.
CR  - 9. Cherian A, Thomas SV. Central nervous system tuberculosis. Afr Health Sci. 2011;11:116-125.
CR  - 10. Keegan M, Pineda AA, McClelland RL, et al. Plasma exchange for severe attacks of CNS demyelination: predictors of response. Neurology. 2002;58:143-148.
CR  - 11. Sonneville R, Demeret S, Klein I, et al. Acute disseminated encephalomyelitis in the intensive care unit: clinical features and outcome of 20 adults. Intensive Care Med. 2008;34:528- 532.
UR  - https://doi.org/10.5799/jmid.328766
L1  - https://dergipark.org.tr/tr/download/article-file/325328
ER  -