TY - JOUR TT - Effects of Caffeine on Human Health AU - Özpalas, Beyza AU - Özer, Emir Ayşe PY - 2017 DA - December Y2 - 2017 DO - 10.17100/nevbiltek.331845 JF - Nevşehir Bilim ve Teknoloji Dergisi PB - Nevşehir Hacı Bektaş Veli Üniversitesi WT - DergiPark SN - 2148-466X SP - 297 EP - 305 VL - 6 KW - Kafein KW - İnsan Sağlığı KW - Beslenme N2 - Caffeineis one of the most broadly consumed psychoactive material all over the world[1] .Historically, tea and soda are the most oldest beverages including caffeine.Recently, variation of food production, whichcomprise caffeine, has increased such as energy drinks, specialist coffee,potato chips, gum and candy bar[8] . Therefore,theconsumption of caffeine-containing drinks has raised remarkably throughout theworld. Indeed, in recent years, the consumption of caffeine is higher than anyother drug. Nearly 80% of the world’s population consumes caffeine-contaningproducts ever day, with tea (12%), soft drink (16%) and coffee (%71) being themost widely consumed[8,9]. There is an significant increase in caffeine consumption throughtlast century with developing technology and innovative evolution in foodindustry. Actually, the rising demanding of the caffeine contaning productionshas brought along with its likley effects on human health. The present studyreviewed the effects of caffeine consumption on human healthy in terms ofcardiovascular system, anxiety, memory, sleep, depression and agression. CR - Referans1 Amendola, C.A., Gabrieli, J.D.F., Lieberman, H.R., Caffeine’s effects on performance and mood are independent of age and gender. Nutr. Neurosci. 1, 269–280. 1998 CR - Referans2 Amaresh, Nirmala, A. R. Mullaicharam, and Mohanned Abdueghafour El-Khider. "Chemistry and pharmacology of caffeine in different types of tea leaves." International Journal of Nutrition, Pharmacology, Neurological Diseases 1.2 :110, 2011 CR - Referans3 Bonita JS, Mandarano M, Shuta D, Vinson J. Coffee and cardiovascular disease: in vitro, cellular, animal, and human studies. Pharmacol Res; 55:187–98, 2007 CR - Referans4 Cano-Marquina, A. et al. The impact of coffee on health. Maturitas 75, 7–21:6, 2013 CR - Referans5 Chen, Jiang-Fan, Holger K. Eltzschig, and Bertil B. Fredholm. "Adenosine receptors as drug targets—what are the challenges?" Nature reviews Drug discovery 12.4: (265-286, 2013 CR - Referans6 Christensen, Larry, and Ross Burrows. "Dietary treatment of depression." Behavior Therapy 21.2 : 183-193, 1990 CR - Referans7 de Mejia, Elvira Gonzalez, and Marco Vinicio Ramirez-Mares. "Impact of caffeine and coffee on our health." Trends in Endocrinology & Metabolism 25.10: 489-492, 2014 CR - Referans8 Dews, Peter B. "Caffeine." Annual review of nutrition 2.1: 323-341, 1982 Referans D.R. Mazzotti, Diego Robles, et al. "Effects of the adenosine deaminase polymorphism and caffeine intake on sleep parameters in a large population sample." Sleep 34.3: 399-402, 2011 CR - Referans9 Dunwiddie, Thomas V., and Susan A. Masino. "The role and regulation of adenosine in the central nervous system." Annual review of neuroscience 24.1: 31-55, 2001 Referans Edwards, Bonnie. America's Favorite Drug: Coffee and Your Health. Berkeley: Odonian Press, 1992 CR - Referans10 Frary, Carol D., Rachel K. Johnson, and Min Qi Wang. "Food sources and intakes of caffeine in the diets of persons in the United States." Journal of the American Dietetic Association 105.1: 110-113,2005 CR - Referans11 Friedman, M., Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas. Mol. Nutr. Food Res. 51, 116–134, 2007 CR - Referans12 Garattini, Silvio, ed. Caffeine, Coffee and Healht. New York: Raven Press, 1993 CR - Referans13 Graham TE, Helge JW, MacLean DA, et al. Caffeine ingestion does not alter carbohydrate or fat metabolism in human skeletal muscle during exercise. J Physiol (London) 529: 837-47, 2000 CR - Referans14 Graham TE, Spriet LL. Performance and metabolic responses to a high caffeine dose during prolonged exercise. J Appl Physiol 71: 2292-8, 1991 CR - Referans15 Graham TE, Spriet LL. Metabolic, catecholamine, and exercise performance responses to various doses of caffeine. J Appl Physiol 78: 867-74,1995 CR - Referans16 Greer F, McLean C, Graham TE. Caffeine, performance and metabolism during repeated Wingate exercise tests. J Appl Physiol 85: 1502-8, 1998 CR - Referans17 Greer F, Friars D, Graham TE. Comparison of caffeine and theophylline ingestion: exercise metabolism and endurance. J Appl Physiol 89: 1837-44, 2000 CR - Referans18 Heckman, M.A. et al. Energy drinks: an assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States. Compr. Rev. Food Sci. Food Safety 9, 303–317, 2010
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